Search results

60 items matching your search terms.
Filter the results.
Item type













New items since



Sort by relevance · date (newest first) · alphabetically
Researchers clarify role of mutations in glioblastoma
In a preclinical study, researchers led by UNC Lineberger's Ryan Miller, MD, PhD, investigated whether the location of where the mutation occurred within the sequence of the PIK3CA gene affected the mutation’s ability to help drive cancerous growth. They also evaluated whether the location of the mutation would affect the cancer's response to certain treatments.
Located in News
Stem cells show promise as drug delivery tool for childhood brain cancer
UNC Lineberger’s Shawn Hingtgen, PhD, and his collaborators showed they could shrink tumors in laboratory models of medulloblastoma, and extend life. The study, published in PLOS ONE, is a necessary step toward developing clinical trials that would see if the approach works for children.
Located in News
Researchers find potential key to unlocking the immune system in pancreatic cancer
In the journal Cancer Immunology Research, scientists led by UNC Lineberger's Yuliya Pylayeva-Gupta, PhD, revealed that a molecule called interleukin-35 plays a role in suppressing cancer-fighting immune cells in pancreatic cancer.
Located in News
Researchers lay the foundation for personalized immune treatments for leukemia
In the journal Blood Advances, UNC Lineberger’s Ben Vincent, MD, Paul Armistead, MD, PhD, and their collaborators reported early findings from a new study that could aid in the development of immune-based treatments that are tailored to individual leukemia patients who are undergoing stem cell transplantation.
Located in News
Researchers map genetic changes in glioblastoma as it progresses, test potential treatment strategy
In a pair of preclinical studies published in the journal Neuro-Oncology, UNC Lineberger's C. Ryan Miller, MD, PhD, and the Phoenix-based Translational Genomics Research Institute report on the genetic evolution of glioblastoma as it progresses in severity and a potential strategy to treat this often fast-growing brain cancer type.
Located in News
Bladder cancer model could pave the way for better drug efficacy studies
In the journal Cancer Research, UNC Lineberger’s William Y. Kim, MD, Benjamin G. Vincent, MD, and colleagues reported they have developed a mouse model of luminal bladder cancer, one of the two subtypes of advanced bladder cancer. The researchers said this model may help them to determine which patients may respond to immunotherapy treatments called checkpoint inhibitors.
Located in News
UNC Lineberger to use Colon Cancer Coalition grant to promote screening in Eastern North Carolina
UNC Lineberger’s Carolina Cancer Screening Initiative is working in partnership with the Roanoke Chowan Community Health Center in Ahoskie, North Carolina, to improve the colorectal cancer screening rates in a part of the state that has been significantly challenged by this disease.
Located in News
Study finds Fitbits can be used to monitor symptoms in transplant patients
UNC Lineberger researchers say the findings of a new study published in the journal Quality of Life Research indicate that activity trackers could be a useful tool for tracking symptoms and physical function. These trackers may be especially useful for patients who are not able to self-report symptoms using questionnaires because of language barriers, literacy, cognitive or health status.
Located in News
UNC-Chapel Hill spinout company generates more than $108M in stock offering
Founded with support from KickStart Venture Services, a UNC-Chapel Hill program that works to turn University research into new companies, G1 Therapeutics is developing novel therapeutics based on discoveries at UNC Lineberger Comprehensive Cancer Center.
Located in News
Scientists discover interplay of yin-yang antagonists vital for cell division
Although mutated versions of the protein Cdh1 have not been found in cancers, the protein’s degradation at a key moment during the cell cycle may spur on cancerous cell division.
Located in News