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UNC Lineberger researchers develop new approach to identify “drivers” of cancer
UNC Lineberger Comprehensive Cancer Center researchers have developed a new integrated approach to pinpoint the genetic “drivers” of cancer, uncovering eight genes that could be viable for targeted breast cancer therapy. The study, published online August 24 in Nature Genetics, was authored by Michael Gatza, PhD, lead author and post-doctoral research associate; Grace Silva, graduate student; Joel Parker, PhD, director of bioinformatics, UNC Lineberger; Cheng Fan, research associate; and senior author Chuck Perou, PhD, professor of genetics and pathology.
Located in News
Cancer genetics the focus of UNC Lineberger symposium
UNC Lineberger's 39th annual scientific symposium was held April 8-9 at the William and Ida Friday Center for Continuing Education in Chapel Hill.
Located in News
Informatics approach helps doctors, patients make sense of genome data
Chapel Hill, NC – The cost of sequencing the entire human genome, or exome – the regions of the genome that are translated into proteins that affect cell behavior – has decreased significantly, to the point where the cost of looking at the majority of a patient’s genomic data may be less expensive than undertaking one or two targeted genetic tests.
Located in News / 2012 News
Genetic mutations linked to salivary gland tumors may point to new therapies
Faculty members at the University of North Carolina School of Dentistry, The Scripps Research Institute (TSRI) and other institutions have discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer’s underlying genetic causes.
Located in News
Evans talks about DNA analysis on HuffPost Live
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, provided his perspective on a HuffPost Live broadcast that aired on September 24, 2012.
Located in News / 2012 News
UNC researchers find new genetic target for a different kind of cancer drug
Upstream of the proteins that cancer cells use to proliferate sits RBM4, a gene-splicing protein that UNC researcher Zefeng Wang, PhD, discovered is drastically reduced in human lung and breast cancer cells.
Located in News
Jeannette T Bensen
PhD, Research Associate Professor, UNC-Chapel Hill, Cancer Epidemiology
Located in People
The Geneticist
With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.
Located in News
NPR - FDA tells Google-backed 23andMe to stop selling DNA test
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, was quoted on National Public Radio's All Things Considered regarding the Food and Drug Administration's warning letter sent to the company 23andMe demanding that its saliva test be taken off the market.
Located in News
UNC Lineberger to offer sequencing expertise to NCI clinical trials networks
Personalized medicine holds great promise for delivering targeted treatments to patients based on their unique genetic characteristics. Through a $3.5 million, five-year grant from the National Cancer Institute (NCI), UNC Lineberger Comprehensive Cancer Center will provide high-throughput RNA and DNA sequencing and regulatory assistance to partner institutions in the NCI’s new National Clinical Trials Network (NCTN).
Located in News