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UNC researchers identify important step in sperm reprogramming
CHAPEL HILL – When sperm meets egg, the chemical instructions that tag sperm cells must be erased so that human life can start anew. One way these instructions are erased is through demethylation, the removal of specific chemical tags or methyl groups that dot the underlying DNA of cells. Though scientists have known about this phenomenon for a decade, exactly how such “reprogramming” occurs has proved elusive.
Located in News / 2011 News
UNC team reports link between protein overexpression and head and neck cancer outcomes
Chapel Hill - A team of UNC scientists report that in laboratory studies, overexpression of a specific protein could be used as a prognostic marker and as a guide for therapeutic choices for patients with head and neck cancer. Their findings appear in the September 9, 2011 online issue of the journal Clinical Cancer Research.
Located in News / 2011 News
UNC spin-off receives $3M Small Business Innovation Research grant
Chapel Hill, NC – G-Zero Therapeutics, an RTP company started in 2008 based on technologies from the University of North Carolina at Chapel Hill, has been awarded a $3 million Phase II Small Business Innovation Research Grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.
Located in News / 2011 News
UNC scientists offer first evidence of using biologically targeted nanoparticles to boost radiation therapy effects
Chapel Hill - Making a tumor more sensitive to radiotherapy is a primary goal of combining chemo and radiation therapy to treat many types of cancer, but with the chemotherapy drugs come unwanted side effects.
Located in News / 2011 News
Study links chemotherapy response to heritable factors
Findings guide future research on chemotherapy resistance
Located in News / 2011 News
No evidence for potential competition between human papillomavirus types in men
Chapel Hill - The Centers for Disease Control and Prevention Advisory Committee on Immunization Practices recently recommended that teenage boys be vaccinated against the human papillomavirus.
Located in News / 2011 News
Scarring a necessary evil to prevent further damage after heart attack
CHAPEL HILL, N.C. – After a heart attack, the portions of the heart damaged by a lack of oxygen become scar tissue. Researchers have long sought ways to avoid this scarring, which can harden the walls of the heart, lessen its ability to pump blood throughout the body and eventually lead to heart failure. But new research from the University of North Carolina at Chapel Hill School of Medicine shows that interrupting this process can weaken heart function even further.
Located in News / 2011 News
Gershon receives grant to study brain tumor, develop novel therapy
Timothy Gershon, MD, PhD, assistant professor of neurology, has received a four-year National Institutes of Health Mentored Clinical Scientist Research Career Development Award grant from the National Institute of Neurologic Disease and Stroke.
Located in News / 2012 News
Small DNA circles found outside the chromosomes in mammalian cells and tissues, including human cells
CHAPEL HILL, N.C. – Researchers from the University of North Carolina at Chapel Hill have helped identify a new DNA entity in mammalian cells and provided evidence that their generation leaves behind deletions in different locations of the cells’ genetic program, or genome.
Located in News / 2012 News
Hematologic malignancies rapidly increasing and unaddressed in sub-Saharan Africa
UNC-led team offers clinical, research agenda
Located in News / 2012 News