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Social networks as important as exercise and diet across the span of our lives
UNC-Chapel Hill researchers show how social relationships reduce health risk in each stage of life in a new study. UNC Lineberger member Yang Claire Yang said the analysis "makes it clear that doctors, clinicians, and other health workers should redouble their efforts to help the public understand how important strong social bonds are throughout the course of all of our lives.”
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Study finds different genetic mutation patterns for HPV-positive throat cancer patients based on smoking history
Researchers at UNC Lineberger Comprehensive Cancer Center have presented preliminary findings from a study examining the genetic alterations in HPV-positive oropharyngeal squamous cell carcinoma, a cancer of the head and neck. The researchers found differences in the genetic mutations of HPV-positive oropharyngeal cancer based on whether patients were heavy versus light smokers.
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Zika, emerging viruses focus of UNC virology seminar
Zika, the virus currently causing worldwide concern due to its alarming connection to a neurological birth disorder, was discussed as part of a presentation on emerging infectious diseases for the UNC Lineberger-led seminar series titled "Virology in Progress." Helen Lazear, PhD, a UNC Lineberger member and an assistant professor in the UNC School of Medicine Department of Microbiology and Immunology, spoke about Zika and noted that experts know relatively little about the virus.
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Physicians issue advice, raise questions about best practices for evaluating blood in the urine as a sign of cancer
A new report from the American College of Physicians’ High Value Care Task Force issues advice for physicians on how to detect and evaluate blood found in the urine, which is known as hematuria. The report, which was first-authored by UNC Lineberger Comprehensive Cancer Center member Dr. Matthew Nielsen, also raises questions about the potential harms associated with diagnostic tests that are commonly employed to evaluate this condition.
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Using new drug screening tool, UNC researchers identify potential treatments for Ewing sarcoma
In a first-of-its-kind-study, researchers have discovered and applied a new screening technique capable of testing thousands of potential drug compounds to see if those compounds can reverse abnormal DNA unwinding in Ewing sarcoma, a bone and soft tissue cancer that’s most common in teens and young adults.
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UNC Startup Receives Federal Grant to Kick-Start Cancer Research Commercialization
G-Zero Therapeutics funded under Qualifying Therapeutic Discovery Project
Located in News / 2011 News
UNC experts discover colorectal cancer biomarker, potential personalized treatment
In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.
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Preclinical study finds no benefit for diabetes drug in pancreatic cancer
UNC Lineberger researchers found in a study published in PLOS ONE that the diabetes drug metformin failed to show any benefit against pancreatic cancer, despite excitement about the drug for potential anti-cancer benefits. They believe the study shows the importance of testing new therapies in preclinical animal models that incorporate actual tumor tissue to better predict patient response.
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UNC experts talk ‘Cancer Moonshot’ with Vice President Biden
As part of the “Cancer Moonshot” federal initiative to spur breakthroughs in cancer research, Biden hosted a roundtable discussion on Wednesday at the Duke University School of Medicine that featured cancer experts and leaders from UNC. Among the experts chosen for the panel were Stephanie Wheeler, PhD, UNC Lineberger member and assistant professor of health policy and management at the UNC Gillings School of Global Public Health and Niklaus Steiner, UNC-Chapel Hill professor and co-founder of the Chapel Hill-based Be Loud! Sophie Foundation, which supports adolescents and young adults with cancer.
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Study finds need for improved end-of-life care for parents with terminal cancer
Based on a survey of widowed fathers who had lost a spouse to cancer, UNC Lineberger researchers reported in the journal BMJ Palliative Care that additional research and improved end-of-life care are needed to specifically help dying parents as well as their families.
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