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Using software, researchers predict tumor markers that could be immune targets
UNC Lineberger researchers led by Benjamin Vincent, MD, reported preliminary findings at the 59th ASH Annual Meeting in Atlanta that are an early step in the overall plan to use the software’s predictions to develop immune-based therapies for leukemia.
Located in News
Biological factors don't completely explain racial disparities for ‘good prognosis’ breast cancer
The biological features of patients’ tumors partially explained a racial disparity for women with hormone receptor-positive, HER2-negative breast cancer, but UNC Lineberger researchers led by Katherine Reeder-Hayes, MD, MBA, MSc, said it didn’t explain it completely. The preliminary findings were reported at the 2017 San Antonio Breast Cancer Symposium.
Located in News
NCI grant to help more cancer patients become tobacco-free
A grant from the National Cancer Institute will help expand tobacco cessation programs for cancer patients at the N.C. Cancer Hospital.
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Timing could matter to how responsive cancer cells are to treatment, study suggests
In a new study published in Cell Systems, UNC Lineberger's Jeremy Purvis, PhD, and colleagues report that the timing of when DNA damage occurs within these different checkpoints matters to a cell’s fate.
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Using new knowledge about cell division, researchers look to improve chemotherapy effects
A study led by UNC Lineberger member Michael J. Emanuele, PhD, was featured on the cover of The Journal of Biological Chemistry. The researchers uncovered new details about a protein called NUSAP1 during chromosome segregation, and offered a possible way to sensitize cancer cells to a particular type of chemotherapy.
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To improve melanoma treatment, researchers look to block deletion of ‘self-reactive’ immune cells
UNC Lineberger researchers led by Maureen Su, MD, report on a potential new way to fight melanoma by blocking one of the immune system’s checks and balances.
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Located in Newsroom / UNC Lineberger in the News
Innovative cancer data resource expands, gains a new name
Academics and policymakers are using the Cancer Information & Population Health Resource, or CIPHR, to knit together data from multiple public and private sources to examine a wide range of complex issues tied to improving cancer outcomes in North Carolina.
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Study sheds light on why some breast cancers have limited response to immunotherapy
Jonathan Serody, MD, Benjamin Vincent, MD, and a team of UNC Lineberger investigators published findings in the Journal of Clinical Investigation that may explain why drugs designed to unleash the immune system against cancer were ineffective in treating a type of triple negative breast cancer. They determined “claudin-low” tumors were releasing a chemical signal to attract regulatory T-cells, which prevented the immune system from rejecting the cancer.
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Kim senior authors study in JCO Precision Oncology
William Y. Kim, MD, has published a study in JCO Precision Oncology that uncovered possible treatment approaches for urachal adenocarcinoma, a rare bladder cancer.
Located in Newsletters / / Honors and Awards / 2017