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Researchers define structure, function of enzyme key to blood cancers
In the journal Nature, UNC Lineberger's Greg Wang, PhD, and colleagues reported findings about the structure and function of the DNMT3A enzyme complex, which helps control gene expression.
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UNC Lineberger to use Colon Cancer Coalition grant to promote screening in Eastern North Carolina
UNC Lineberger’s Carolina Cancer Screening Initiative is working in partnership with the Roanoke Chowan Community Health Center in Ahoskie, North Carolina, to improve the colorectal cancer screening rates in a part of the state that has been significantly challenged by this disease.
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UNC Lineberger awards $1.1M in developmental research grants
Eleven projects -- four basic science, four clinical/translational science and three population science -- were selected from a pool of 60 applicants from a broad range of disciplines.
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Narrowing the gap toward precision medicine for pancreatic cancer
To improve treatment and our understanding of one of the deadliest cancers in the United States, UNC Lineberger's Jen Jen Yeh, MD, was involved in two studies that take different approaches to precision medicine for pancreatic cancer.
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Skin cancer treatment selfie goes viral, has public health lessons
Researchers led by UNC Lineberger's Seth Noar, PhD, analyzed the impact of one viral social media post in generating awareness about skin cancer.
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Using software, researchers predict tumor markers that could be immune targets
UNC Lineberger researchers led by Benjamin Vincent, MD, reported preliminary findings at the 59th American Society for Hematology Annual Meeting in Atlanta that are an early step in the overall plan to use the software’s predictions to develop immune-based therapies for leukemia.
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Biological factors don't completely explain racial disparities for ‘good prognosis’ breast cancer
The biological features of patients’ tumors partially explained a racial disparity for women with hormone receptor-positive, HER2-negative breast cancer, but UNC Lineberger researchers led by Katherine Reeder-Hayes, MD, MBA, MSc, said it didn’t explain it completely. The preliminary findings were reported at the 2017 San Antonio Breast Cancer Symposium.
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NCI grant to help more cancer patients become tobacco-free
A grant from the National Cancer Institute will help expand tobacco cessation programs for cancer patients at the N.C. Cancer Hospital.
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Timing could matter to how responsive cancer cells are to treatment, study suggests
In a new study published in Cell Systems, UNC Lineberger's Jeremy Purvis, PhD, and colleagues report that the timing of when DNA damage occurs within these different checkpoints matters to a cell’s fate.
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Using new knowledge about cell division, researchers look to improve chemotherapy effects
A study led by UNC Lineberger member Michael J. Emanuele, PhD, was featured on the cover of The Journal of Biological Chemistry. The researchers uncovered new details about a protein called NUSAP1 during chromosome segregation, and offered a possible way to sensitize cancer cells to a particular type of chemotherapy.
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