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Partnering with IBM and Watson to accelerate DNA analysis and inform personalized treatment
UNC Lineberger will be one of more than a dozen leading cancer centers tapping IBM's Watson to accelerate DNA analysis and inform personalized treatment options for patients. The project is part of IBM’s broader Watson Health initiative to advance patient-centered care and improve health.
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UNC researchers create DNA repair map of the entire human genome
The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.
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Cancer genetics the focus of UNC Lineberger symposium
UNC Lineberger's 39th annual scientific symposium was held April 8-9 at the William and Ida Friday Center for Continuing Education in Chapel Hill.
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Researchers find new approach to treat drug-resistant HER2-positive breast cancer
Using human cancer cell lines, UNC scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.
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Lower survival rates connected with high-risk melanoma with mutations, study finds
A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.
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Perou recognized as health care innovator, awarded Triangle Business Journal honor
Charles M. Perou, PhD, professor of genetics and pathology at the University of North Carolina School of Medicine and the basic science leader of the UNC Lineberger Comprehensive Cancer Center Breast Cancer Research Program, has been acknowledged as a health care innovator by the Triangle Business Journal. During an awards ceremony on Thursday, Perou was selected from a pool of candidates as the finalist in the 2015 TBJ Health Care Heroes – Innovator category.
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Researchers pinpoint two genes that trigger severest form of ovarian cancer
UNC geneticists create the first mouse model of ovarian clear cell carcinoma; show how a known drug can suppress tumor growth.
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Evans co-authors commentary in JAMA
UNC Lineberger Comprehensive Cancer Center member Jim Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine and director of clinical cancer genetics, has co-authored a commentary on proposed US Food and Drug Administration (FDA) regulation of genetic testing in the Journal of the American Medical Association (JAMA).
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UNC researchers create new technique to silence leading cancer-causing gene
UNC Lineberger researchers and colleagues at The University of Texas MD Anderson Cancer Center have developed a new approach to block the KRAS oncogene, one of the most frequently mutated genes in human cancer. The approach, led by Chad Pecot, MD, an assistant professor of medicine at UNC, offers another route to attack KRAS, which has proven to be an elusive and frustrating target for drug developers.
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The Geneticist
With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.
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