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'60 Minutes' profiles how UNC Lineberger is leveraging artificial intelligence
CBS's "60 Minutes" came to UNC Lineberger to learn how researchers are using IBM Watson to cull through and generate useful clinical insights from massive amounts of genetic data.
Located in News
Aggressive breast cancer grows faster in obese environment
In an abstract presented at the American Association for Cancer Research Annual Meeting 2017, UNC Lineberger's Liza Makowski, PhD, reported her and her colleagues' preliminary findings that breast cancer cells grew larger when they were transplanted into fatty, obese tissue.
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Cancer cells continue abnormal growth by activating error-prone DNA synthesis
UNC Lineberger researchers led by Cyrus Vaziri, PhD, describe the discovery of how a specific cellular protein present in cancer cells triggers a repair mechanism that allows them to DNA damage tolerance and abnormal growth.
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Genetic alterations more common in tumors of older patients with metastatic breast cancer
In preliminary findings presented at the 2016 San Antonio Breast Cancer Symposium, researchers showed that older patients were as likely as younger patients to receive targeted therapy and enroll in therapeutic trials based on their sequencing results.
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Images of health risks make indoor tanning messages more effective
UNC Lineberger's Seth Noar, PhD, and colleagues report in a new study that anti-tanning bed messages with images showing longer-term health effects, such as skin cancer or wrinkles, produced greater negative emotional reactions and higher ratings of effectiveness in a survey of female college students than text-only messages.
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In ovarian cancer, researchers uncover new drivers of cell division
UNC Lineberger's Michael J. Emanuele, PhD, and colleagues have identified a key activator that can turn on FoxM1, a protein that drives expression of genes that help cells replicate and divide, a finding they published in the journal Molecular and Cellular Biology. They also discovered, paradoxically, that the activator for FoxM1 is also responsible for turning this protein off.
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Insurance, distance to care can be barriers to breast reconstruction
Researchers say breast reconstruction can help with self-esteem, sexuality and body image after cancer treatment. But a UNC Lineberger study led by Michelle Roughton, MD, has found that the type of insurance a woman has as well as distance to a plastic surgeon's office can be barriers to the procedure.
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New insights into side effects can help prostate cancer patients choose treatments
In the Journal of the American Medical Association, a study led by UNC Lineberger member Ronald C. Chen, MD, MPH, examines quality-of-life outcomes for modern treatment choices most patients will face, including active surveillance, radical prostatectomy, external beam radiation treatment, and brachytherapy.
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New models of kidney cancer may drive immunotherapy research
UNC Lineberger member William Y. Kim, MD, and his colleagues report in the journal Nature Communications they have created laboratory models of both papillary and clear cell renal cell carcinoma that faithfully mimic the genetic changes seen in tumors of patients with these cancers.
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New UNC Lineberger faculty recruited to launch T-cell cancer therapy trials
Two new faculty members have joined the UNC Lineberger Comprehensive Cancer Center to help launch groundbreaking immunotherapy clinical trials that will test an experimental treatment in which patients’ own immune cells are genetically engineered to fight their cancer.
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