In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.
Kirsten Bryant, PhD, a cancer researcher and postdoctoral fellow at the UNC Lineberger Comprehensive Cancer Center, and Channing Der, PhD, a UNC Lineberger member and the Sarah Graham Kenan Professor of Pharmacology, shared personal stories of why they're driven to fight pancreatic cancer at a breakfast in Durham on Tuesday.
In a first-of-its-kind-study, researchers have discovered and applied a new screening technique capable of testing thousands of potential drug compounds to see if those compounds can reverse abnormal DNA unwinding in Ewing sarcoma, a bone and soft tissue cancer that’s most common in teens and young adults.
A preclinical study led by a UNC Lineberger Comprehensive Cancer Center researcher found that skin cells turned cancer-killing stem cells hunt down and destroy the deadly remnants inevitably left behind when a brain tumor is surgically removed.
Albert S. Baldwin, UNC Lineberger’s associate director of basic research and the William Rand Kenan Professor of Biology at UNC, will receive nearly $5.9 million across seven years as a recipient of the National Cancer Institute's Outstanding Investigator Award. He is the second UNC Lineberger researcher to receive the award behind Stephen Hursting, who is studying the link between obesity and cancer.
Eric Strand, currently a student at the UNC School of Medicine, has quite a story to tell. The Green Beret medic -turned aspiring oncologist talked about second chances with attendees of the Lineberger Club Brunch and Basketball Game on Saturday, Feb. 20.