Recent News

UNC Lineberger researchers uncover promising direction for the treatment of pancreatic cancers driven by KRAS mutation

UNC Lineberger researchers uncover promising direction for the treatment of pancreatic cancers driven by KRAS mutation

In the journal Cancer Cell, UNC Lineberger researchers report findings of a promising strategy to treat KRAS-mutant pancreatic cancers. Preclinical studies showed promise for using a type of investigational drug that works by inhibiting the protein ERK, the last of a series of signals of a signaling pathway that drives drive abnormal growth of cells with KRAS mutations.

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Study finds gaps in patient knowledge of breast reconstruction surgery and complications

Study finds gaps in patient knowledge of breast reconstruction surgery and complications

Researchers at UNC Lineberger Comprehensive Cancer Center found that breast cancer patients surveyed about their knowledge of breast reconstruction were only moderately informed about the procedure, and their knowledge of complications was low. The study, published in the journal Annals of Surgery, surveyed 126 breast cancer patients planning to undergo mastectomy at the N.C. Cancer Hospital.

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DeSimone to receive National Medal of Technology and Innovation

DeSimone to receive National Medal of Technology and Innovation

Joseph DeSimone is the Chancellor’s Eminent Professor of Chemistry in the College of Arts and Sciences at the University of North Carolina at Chapel Hill and a member of UNC Lineberger. He will be honored in a ceremony at the White House.

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Researchers identify DNA repair enzyme as potential brain cancer drug target

Researchers identify DNA repair enzyme as potential brain cancer drug target

In the journal Cell Reports, UNC Lineberger researchers report that when they removed Dicer from preclinical models of medulloblastoma, a common type of brain cancer in children, they found high levels of DNA damage in the cancer cells. The tumor cells were smaller, and also more sensitive to chemotherapy.

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Social networks as important as exercise and diet across the span of our lives

Social networks as important as exercise and diet across the span of our lives

UNC-Chapel Hill researchers show how social relationships reduce health risk in each stage of life in a new study. UNC Lineberger member Yang Claire Yang said the analysis "makes it clear that doctors, clinicians, and other health workers should redouble their efforts to help the public understand how important strong social bonds are throughout the course of all of our lives.”

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UNC Lineberger researchers reveal clues to breast cancer metastasis at San Antonio Breast Cancer Symposium

UNC Lineberger researchers reveal clues to breast cancer metastasis at San Antonio Breast Cancer Symposium

Researchers and physicians from around the globe convened Dec. 8-12 for the 2015 San Antonio Breast Cancer Symposium at the Henry B. Gonzalez Convention Center in San Antonio, Texas. UNC Lineberger researchers presented preliminary findings from studies focused on genomic clues to breast cancer metastasis, the link between obesity and cancer, and on the use of genetic sequencing to find targeted treatments for individual patients.

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