Recent News

New compound is effective against drug-resistant leukemia, preclinical study finds

New compound is effective against drug-resistant leukemia, preclinical study finds

Researchers at UNC Lineberger and at other institutions developed a new potential treatment for acute myeloid leukemia. In the journal JCI Insight, they report that the compound MRX-2843 more than doubled the median days of survival in laboratory models with a drug-resistant form of the disease.

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UNC experts discover colorectal cancer biomarker, potential personalized treatment

UNC experts discover colorectal cancer biomarker, potential personalized treatment

In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.

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Researchers share stories of their drive to fight pancreatic cancer

Researchers share stories of their drive to fight pancreatic cancer

Kirsten Bryant, PhD, a cancer researcher and postdoctoral fellow at the UNC Lineberger Comprehensive Cancer Center, and Channing Der, PhD, a UNC Lineberger member and the Sarah Graham Kenan Professor of Pharmacology, shared personal stories of why they're driven to fight pancreatic cancer at a breakfast in Durham on Tuesday.

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Using new drug screening tool, UNC researchers identify potential treatments for Ewing sarcoma

Using new drug screening tool, UNC researchers identify potential treatments for Ewing sarcoma

In a first-of-its-kind-study, researchers have discovered and applied a new screening technique capable of testing thousands of potential drug compounds to see if those compounds can reverse abnormal DNA unwinding in Ewing sarcoma, a bone and soft tissue cancer that’s most common in teens and young adults.

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UNC researchers make groundbreaking discovery, use skin cells to kill cancer

UNC researchers make groundbreaking discovery, use skin cells to kill cancer

A preclinical study led by a UNC Lineberger Comprehensive Cancer Center researcher found that skin cells turned cancer-killing stem cells hunt down and destroy the deadly remnants inevitably left behind when a brain tumor is surgically removed.

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Baldwin receives NCI Outstanding Investigator Award

Baldwin receives NCI Outstanding Investigator Award

Albert S. Baldwin, UNC Lineberger’s associate director of basic research and the William Rand Kenan Professor of Biology at UNC, will receive nearly $5.9 million across seven years as a recipient of the National Cancer Institute's Outstanding Investigator Award. He is the second UNC Lineberger researcher to receive the award behind Stephen Hursting, who is studying the link between obesity and cancer.

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