UNC Lineberger News

The Geneticist

The Geneticist

With his selection to the NIH Council of Councils, Terry Magnuson, PhD, becomes the first UNC scientist appointed to the board dedicated to funding the biggest ideas in medical research.

The Geneticist - Read More…

UNC researchers find final pieces to the circadian clock puzzle

UNC researchers find final pieces to the circadian clock puzzle

Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.

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Damania appointed Assistant Dean for Research

Damania appointed Assistant Dean for Research

Blossom Damania, PhD, professor of microbiology and immunology, has been named Assistant Dean for Research at the UNC School of Medicine, effective immediately.

Damania appointed Assistant Dean for Research - Read More…

Basch contributes to new ASCO guidelines for prostate cancer treatment

Basch contributes to new ASCO guidelines for prostate cancer treatment

New clinical guidelines have been announced for the treatment of men with metastatic castration-resistant prostate cancer (CRPC) by the American Society of Clinical Oncology (ASCO) and Cancer Care Ontario (CCO). Ethan Basch, MD, director of the Cancer Outcomes Research Program at UNC Lineberger Comprehensive Cancer Center, served as the co-chair of the ASCO/CCO expert panel that developed the guideline.

Basch contributes to new ASCO guidelines for prostate cancer treatment - Read More…

UNC researchers find new genetic target for a different kind of cancer drug

UNC researchers find new genetic target for a different kind of cancer drug

Upstream of the proteins that cancer cells use to proliferate sits RBM4, a gene-splicing protein that UNC researcher Zefeng Wang, PhD, discovered is drastically reduced in human lung and breast cancer cells.

UNC researchers find new genetic target for a different kind of cancer drug - Read More…

Popular cancer drug target implicated in cardiovascular defects

Popular cancer drug target implicated in cardiovascular defects

Research led by UNC’s Kathleen Caron, PhD, shows that halting the protein CXCR7 leads to over activation of adrenomedullin, a hormone needed at proper levels for normal cardiovascular development

Popular cancer drug target implicated in cardiovascular defects - Read More…

Changing the face of clinical trials

Changing the face of clinical trials

UNC Lineberger secures three major NCI grants to advance the nation’s clinical trials program.

Changing the face of clinical trials - Read More…

Anders presents at 13th Annual Round Asia Oncology Forum

Anders presents at 13th Annual Round Asia Oncology Forum

Carey Anders, MD, UNC Lineberger member and associate professor, was a presenter and moderator at The 13th Annual Round Asia Oncology Forum (RAOF) in Hong Kong on August 29 - 30, 2014. The theme of this year’s forum was “Expanding our armory in personalized cancer treatment.”

Anders presents at 13th Annual Round Asia Oncology Forum - Read More…

Eshelman gives $3 million gift to Center for Integrative Chemical Biology and Drug Discovery

Eshelman gives $3 million gift to Center for Integrative Chemical Biology and Drug Discovery

The UNC Eshelman School of Pharmacy has received a $3 million gift from philanthropist and pharmaceutical-industry executive Fred Eshelman. Eshelman’s gift will support the work of the School’s Center for Integrative Chemical Biology and Drug Discovery, led by UNC Lineberger member Stephen Frye, PhD. The center is dedicated to evaluating and developing potential drug targets discovered by UNC faculty.

Eshelman gives $3 million gift to Center for Integrative Chemical Biology and Drug Discovery - Read More…

2014 University Cancer Research Fund Innovation Awards announced

Six researchers have been awarded 2014 University Cancer Research Fund (UCRF) Innovation Awards for promoting innovative and new ideas in cancer research at the University of North Carolina at Chapel Hill.

2014 University Cancer Research Fund Innovation Awards announced - Read More…

Field of Hope honors cancer survivors and raises money for Kay Yow Cancer Fund

Field of Hope honors cancer survivors and raises money for Kay Yow Cancer Fund

UNC Health Care and Rex Healthcare co-sponsored “Field of Hope” at the Durham Bulls game on Saturday, August 23 with a portion of special ticket sales going to the Kay Yow Cancer Fund.

Field of Hope honors cancer survivors and raises money for Kay Yow Cancer Fund - Read More…

Lung Cancer Initiative of NC Hosts 4th Lung Cancer Advocacy Summit

Lung Cancer Initiative of NC Hosts 4th Lung Cancer Advocacy Summit

The Lung Cancer Initiative of NC hosted a statewide Lung Cancer Summit on August 23 at the N.C. Cancer Hospital. Lung cancer advocates were bolstered with training, resources, knowledge and the courage to take action. UNC Lineberger Comprehensive Cancer Center was the Host Sponsor of the event.

Lung Cancer Initiative of NC Hosts 4th Lung Cancer Advocacy Summit - Read More…

The Ras Tracker

The Ras Tracker

For more than 20 years, Sharon Campbell, PhD, has been studying Ras, a protein implicated in 30 percent of all cancers. Now she’s on the hunt for alternative ways to shut the protein down.

The Ras Tracker - Read More…

UNC researchers trade lab coats for running shoes

UNC researchers trade lab coats for running shoes

Kirsten Bryant, PhD, was recently recognized by the Pancreatic Cancer Action Network for her dual role in the fight against pancreatic cancer.

UNC researchers trade lab coats for running shoes - Read More…

UNC Lineberger researchers develop new approach to identify “drivers” of cancer

UNC Lineberger Comprehensive Cancer Center researchers have developed a new integrated approach to pinpoint the genetic “drivers” of cancer, uncovering eight genes that could be viable for targeted breast cancer therapy. The study, published online August 24 in Nature Genetics, was authored by Michael Gatza, PhD, lead author and post-doctoral research associate; Grace Silva, graduate student; Joel Parker, PhD, director of bioinformatics, UNC Lineberger; Cheng Fan, research associate; and senior author Chuck Perou, PhD, professor of genetics and pathology.

UNC Lineberger researchers develop new approach to identify “drivers” of cancer - Read More…

UNC researchers lead project to sequence rare kidney cancer

UNC researchers lead project to sequence rare kidney cancer

An international scientific collaboration led by researchers at UNC has revealed new insights into the unique genetic alterations that contribute to a rare form of kidney cancer.

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Older Patients with Limited Life Expectancy Still Receive Cancer Screenings

Older Patients with Limited Life Expectancy Still Receive Cancer Screenings

A substantial number of older patients with limited life expectancy receive routine screenings for prostate, breast, cervical and colorectal cancer even though the procedures are unlikely to benefit them, according to research conducted at the University of North Carolina at Chapel Hill.

Older Patients with Limited Life Expectancy Still Receive Cancer Screenings - Read More…

UNC Lineberger announces Developmental Research Award winners

UNC Lineberger Comprehensive Cancer Center has awarded nine researchers with Developmental Research Awards to support their work in advancing the fields of clinical/translational and population science cancer research.

UNC Lineberger announces Developmental Research Award winners - Read More…

UNC Cancer Care’s statewide multidisciplinary approach highlighted in Health Leaders Media

UNC Cancer Care’s statewide multidisciplinary approach highlighted in Health Leaders Media

A recent article published in the July/August 2014 issue of Health Leaders magazine focuses on some of UNC Lineberger’s strengths that rank it among the nation’s leading cancer centers.

UNC Cancer Care’s statewide multidisciplinary approach highlighted in Health Leaders Media - Read More…

U.S. News article highlights nation’s top cancer centers, cites UNC Lineberger

A recent U.S. News & World Report article highlights the nation’s cancer centers, focusing especially on those that the National Cancer Institute has designated as comprehensive cancer centers, citing advantages of patients being seen at or referred to these sites, including advances in technology and collaboration.

U.S. News article highlights nation’s top cancer centers, cites UNC Lineberger - Read More…

Largest cancer genetic analysis reveals new way of classifying cancer

Largest cancer genetic analysis reveals new way of classifying cancer

Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill and other TCGA sites, not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development.

Largest cancer genetic analysis reveals new way of classifying cancer - Read More…

Genetic mutations linked to salivary gland tumors may point to new therapies

Genetic mutations linked to salivary gland tumors may point to new therapies

Faculty members at the University of North Carolina School of Dentistry, The Scripps Research Institute (TSRI) and other institutions have discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer’s underlying genetic causes.

Genetic mutations linked to salivary gland tumors may point to new therapies - Read More…

Remembering Dr. Feng Liu

Remembering Dr. Feng Liu

Feng Liu, PhD, a research professor in the Division of Molecular Pharmaceutics and UNC Lineberger member, died tragically Thursday, July 24, after being assaulted and robbed while walking in a neighborhood near campus. Liu was a dedicated colleague, educator and researcher focused on gene and drug delivery.

Remembering Dr. Feng Liu - Read More…

UNC researchers discover how Hepatitis C virus persists for years

UNC researchers discover how Hepatitis C virus persists for years

Hepatitis C virus (HCV) lingers in the human body for years, slowly damaging the liver and leading to liver diseases such as hepatitis, cirrhosis and liver cancer, which is often fatal. Research conducted at the University of North Carolina at Chapel Hill has discovered a mechanism that facilitates the virus achieving this life-long persistence. Chronic HCV infection is the leading cause of liver cancer in the United States.

UNC researchers discover how Hepatitis C virus persists for years - Read More…

UNC jumps 5 slots in 2014–15 U.S. News & World Report cancer rankings

UNC jumps 5 slots in 2014–15 U.S. News & World Report cancer rankings

UNC Hospitals is nationally ranked in cancer, taking the number 38th spot in the country. The latest ranking is up from 43rd in 2013.

UNC jumps 5 slots in 2014–15 U.S. News & World Report cancer rankings - Read More…

Amelio joins UNC School of Dentistry, UNC Lineberger

Amelio joins UNC School of Dentistry, UNC Lineberger

Dr. Antonio (Tony) Amelio recently began his joint appointment as assistant professor in the Department of Dental Ecology at the UNC School of Dentistry and as associate member at UNC Lineberger.

Amelio joins UNC School of Dentistry, UNC Lineberger - Read More…

Campbell awarded 2014 Battle Cancer Research Award

Campbell awarded 2014 Battle Cancer Research Award

Sharon Campbell, professor of biochemistry and biophysics, has been awarded the 2014 Hyman L. Battle Distinguished Cancer Research Award by the UNC School of Medicine. The award recognizes sustained, exceptional cancer research over a career by School of Medicine faculty.

Campbell awarded 2014 Battle Cancer Research Award - Read More…

Kim receives 2014 Bladder Cancer Research Innovation Award

Kim receives 2014 Bladder Cancer Research Innovation Award

The Bladder Cancer Advocacy Network (BCAN) has awarded William Kim, MD, associate professor of medicine, urology, and genetics, University of North Carolina at Chapel Hill and UNC Lineberger Comprehensive Cancer Center, with the 2014 Bladder Cancer Research Innovation Award to support his project “Immune Characterization of High-Grade Bladder Cancer.”

Kim receives 2014 Bladder Cancer Research Innovation Award - Read More…

UNC Lineberger researchers recognized by Thomson-Reuters as highly influential

UNC Lineberger researchers recognized by Thomson-Reuters as highly influential

Six UNC Lineberger members are among the most often-cited scientists in the world, according to the Thomson Reuters 2014 Highly Cited Researchers list.

UNC Lineberger researchers recognized by Thomson-Reuters as highly influential - Read More…

N.C. Medical Journal July/August issue highlights UNC Lineberger cancer research

N.C. Medical Journal July/August issue highlights UNC Lineberger cancer research

Cancer care in North Carolina is the focus of the July/August issue of the North Carolina Medical Journal (NCMJ). The issue, co-guest-edited by UNC Lineberger Comprehensive Cancer Center members Ethan Basch, MD, and Stephanie Wheeler, PhD, MPH, features articles on a wide variety of issues that determine how the state’s residents receive treatment for cancer.

N.C. Medical Journal July/August issue highlights UNC Lineberger cancer research - Read More…

Study in mice finds weight loss reduces progression of basal-like breast cancer

Obesity, epidemic in the U.S. and worldwide, is one of the important modifiable risk factors for breast cancer, especially a particularly aggressive subtype called basal-like breast cancer (BBC). Population studies have suggested that lifestyle interventions, including weight loss, could prevent a large proportion of this type of cancer; however, data on the effect of weight loss on BBC risk are limited and the mechanisms involved uncertain.

Study in mice finds weight loss reduces progression of basal-like breast cancer - Read More…

Doctors not adequately informing patients of cancer screening pros and cons, study finds

Though cancer screening has come a long way, physicians still do not thoroughly discuss with patients the advantages and disadvantages of these procedures before decisions are made to undergo the screenings, according to a new study co-authored by a physician from The University of North Carolina at Chapel Hill’s Gillings School of Global Public Health.

Doctors not adequately informing patients of cancer screening pros and cons, study finds - Read More…

UNC-developed tools improve accuracy of cancer DNA sequencing

The ability of researchers and physicians to use DNA sequencing to pinpoint the genetic mutations that cause cancer has led to greater understanding of the causes of the disease and development of drugs that treat tumors by targeting specific mutations. A pair of papers published by researchers at the UNC Lineberger Comprehensive Cancer Center reveal new tools that can improve the accuracy of tumor sequencing.

UNC-developed tools improve accuracy of cancer DNA sequencing - Read More…

Chen chosen for ASCO Leadership Development Program

The American Society of Clinical Oncology (ASCO) has chosen Ronald Chen, MD, MPH, assistant professor of radiation oncology and member of the UNC Lineberger Comprehensive Cancer Center, as a member of the 2014-2015 ASCO Leadership Development Program.

Chen chosen for ASCO Leadership Development Program - Read More…

WRAL story highlights bladder cancer vaccine study at UNC

A story that ran on Raleigh-based CBS affiliate WRAL focuses on a new bladder cancer vaccine being studied at UNC, called Impact Therapy. The vaccine works to target cancer cells with minimal side effects.

WRAL story highlights bladder cancer vaccine study at UNC - Read More…

Shared decision making still lacking for cancer screening

NEW YORK (Reuters Health) - When it comes to cancer screening, doctors often do not adequately discuss the balance of pros and cons with their patients, a new study suggests.

Shared decision making still lacking for cancer screening - Read More…

Indian delegation tours UNC Lineberger

A delegation from the Tata Memorial Centre cancer hospital in Mumbai, India visited the UNC Lineberger Comprehensive Cancer Center as part of a U.S. tour visiting comprehensive cancer centers. The visit, sponsored through the National Cancer Institute’s (NCI) Liaison for International Partnerships, was intended to share knowledge about how American universities and hospitals operate a comprehensive cancer center.

Indian delegation tours UNC Lineberger - Read More…

BB&T “Comfort Cart” comes with care

Close to a dozen BB&T employees recently gave their morning to volunteer at the Patient and Family Resource Center (PFRC) at the N.C. Cancer Hospital. They came to deliver the BB&T “Comfort Cart,” a rolling cart filled with snacks to comfort and sustain cancer patients and their families while they are at the cancer hospital. They brought enough granola bars, nutrition shakes and other non-perishable snacks to keep the cart stocked for months. They also brought the gifts of housekeeping and organization.

BB&T “Comfort Cart” comes with care - Read More…

UNC/Rex team up for 2014 Susan G. Komen Triangle Race for the Cure

UNC/Rex team up for 2014 Susan G. Komen Triangle Race for the Cure

The UNC/Rex team joined thousands of cancer survivors and supporters on Saturday, June 14th for the 18th annual Susan G. Komen Triangle Race for the Cure at Meredith College in Raleigh.

UNC/Rex team up for 2014 Susan G. Komen Triangle Race for the Cure - Read More…

Vanderwalde awarded Conquer Cancer Foundation Young Investigator Award

Noam Vanderwalde, MD, a radiation oncology resident at the N.C. Cancer Hospital, was awarded a 2014 Young Investigator Award by the Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO).

Vanderwalde awarded Conquer Cancer Foundation Young Investigator Award - Read More…

UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer

The discovery, from the lab of Brian Strahl, PhD, offers insights for the creation of better, more targeted therapies for various forms of cancer.

UNC researchers pinpoint new role for enzyme in DNA repair, kidney cancer - Read More…

Most Breast Cancer Patients May Not Be Getting Enough Exercise

Physical activity after breast cancer diagnosis has been linked with prolonged survival and improved quality of life, but most participants in a large breast cancer study did not meet national physical activity guidelines after they were diagnosed.

Most Breast Cancer Patients May Not Be Getting Enough Exercise - Read More…

Wheeler and Reeder-Hayes research shows African-American women and those insured by Medicaid less likely to receive endocrine therapy to prevent breast cancer recurrence

New research by Stephanie B. Wheeler, PhD; Katie Reeder-Hayes, MD; and Anne Marie Meyer, PhD, reveals that breast cancer patients insured by Medicaid and African-American breast cancer patients are less likely to receive life-saving endocrine therapy (ET) to prevent cancer recurrence.

Wheeler and Reeder-Hayes research shows African-American women and those insured by Medicaid less likely to receive endocrine therapy to prevent breast cancer recurrence - Read More…

UNC Lineberger members present at 2014 ASCO Annual Meeting

More than 25 members and affiliated physicians of the UNC Lineberger Comprehensive Cancer Center will present their work to the attendees at the 2014 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, being held May 30 through June 3. The annual meeting brings together more than 25,000 oncology professionals to present research and discuss new treatment options.

UNC Lineberger members present at 2014 ASCO Annual Meeting - Read More…

Toxins in the Environment Might Make You Older Than Your Years

CHAPEL HILL, NC - Why are some 75-year-olds downright spry while others can barely get around? Part of the explanation, according to research published today in Cell Press journal "Trends in Molecular Medicine," is differences from one person to the next in exposure to harmful substances in the environment, chemicals such as benzene, cigarette smoke, and even stress.

Toxins in the Environment Might Make You Older Than Your Years - Read More…

2013-2014 University Cancer Research Fund Annual Report now available

The UCRF, a $42 million, state-appropriated fund established in 2007, continues to have a significant impact on cancer research in North Carolina.

2013-2014 University Cancer Research Fund Annual Report now available - Read More…

Marie’s ‘Hike For a Cure’ brings in over $5,000 for bone cancer research at UNC Lineberger

Virginia resident Marie Clem loves to hike. She began the activity as a way to improve her physical and mental health, and it has turned into so much more. On April 26, Marie, alongside family and friends, hiked for a different reason: to fight bone cancer.

Marie’s ‘Hike For a Cure’ brings in over $5,000 for bone cancer research at UNC Lineberger - Read More…

Runner's World article features UNC research on benefits of exercise for breast cancer survivors

An article on the benefits of exercise for breast cancer survivors recently published on the Runner's World website is based off of research published by UNC Lineberger member and Associate Professor of Exercise and Sport Science, Claudio Battaglini, PhD.

Runner's World article features UNC research on benefits of exercise for breast cancer survivors - Read More…