UNC Lineberger News

Norman E. Sharpless, MD, appointed the Wellcome Distinguished Professor in Cancer Research

Norman E. Sharpless, MD, appointed the Wellcome Distinguished Professor in Cancer Research

Chapel Hill, NC – Norman E. “Ned” Sharpless, MD, professor of medicine and genetics and Associate Director for Translational Research at UNC Lineberger Comprehensive Cancer Center has been appointed the Wellcome Distinguished Professor in Cancer Research. The professorship was established by the School of Medicine in 1988 with gifts from the Burroughs Wellcome Fund and the William A. Smith Trust of Wadesboro, NC. The gifts were supplemented by the state of North Carolina the Distinguished Professors Endowment Trust Fund to create the endowed professorship.

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Grant to fund use of kinase test in HER2-positive breast cancer

Grant to fund use of kinase test in HER2-positive breast cancer

Chapel Hill, NC – Susan G. Komen for the Cure® has awarded a grant of almost $900,000 to Lisa A. Carey, MD, and Gary Johnson, PhD, to research clinical applications for the first broad-based test for protein kinase activation and response to inhibitory drugs in HER2-positive breast cancer.

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DNA replication protein also has a role in mitosis, cancer

DNA replication protein also has a role in mitosis, cancer

The finding presents a possible explanation for why so many cancers possess not just genomic instability, but also more or less than the usual 46 DNA-containing chromosomes.

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Study shows benefit of new maintenance therapy for multiple myeloma

Study shows benefit of new maintenance therapy for multiple myeloma

Chapel Hill, NC – Multiple myeloma is a form of cancer where the plasma cells in the bone marrow grow out of control, causing damage to bones as well as predisposing patients to anemia, infection and kidney failure. A medical procedure called autologous hematopoietic stem cell transplantation, commonly known as a stem cell transplant, is frequently an important treatment option for many patients.

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Molecular subtypes and genetic alterations may determine response to lung cancer therapy

Molecular subtypes and genetic alterations may determine response to lung cancer therapy

Chapel Hill - Cancer therapies targeting specific molecular subtypes of the disease allow physicians to tailor treatment to a patient’s individual molecular profile. But scientists are finding that in many types of cancer the molecular subtypes are more varied than previously thought and contain further genetic alterations that can affect a patient’s response to therapy.

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UNC Bone Marrow and Stem Cell Transplantation Program achieves outstanding outcomes

Chapel Hill, NC –A medical procedure called allogeneic hematopoietic cell transplantation, commonly known as a bone marrow or stem cell transplant, is the only known curative option for many patients with life-threatening blood-borne cancers such as leukemia and lymphoma.

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Thriving on science: in depth with Jason Lieb

Thriving on science: in depth with Jason Lieb

Jason Lieb likes to mix it up. A triathlete, he enjoys running, swimming and cycling. In his lab, he works in several model systems: yeast, round worms (C. elegans), fruit flies (Drosophila melanogaster) and human cell lines.

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Postdoctoral fellow receives DOD Visionary Fellowship Award

Postdoctoral fellow receives DOD Visionary Fellowship Award

Idoia Garcia, PhD, a postdoctoral fellow in the lab of Timothy Gershon, MD, PhD, has been awarded a Department of Defense Visionary Postdoctoral Fellowship Award. The peer-reviewed award is intended to support exceptionally talented recent medical or other doctoral graduates in their pursuit of cutting-edge, innovative, high-risk/high-impact cancer research during their postdoctoral fellowship.

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