Hepatitis C virus (HCV) lingers in the human body for years, slowly damaging the liver and leading to liver diseases such as hepatitis, cirrhosis and liver cancer, which is often fatal. Research conducted at the University of North Carolina at Chapel Hill has discovered a mechanism that facilitates the virus achieving this life-long persistence. Chronic HCV infection is the leading cause of liver cancer in the United States.
UNC Hospitals is nationally ranked in cancer, taking the number 38th spot in the country. The latest ranking is up from 43rd in 2013.
Dr. Antonio (Tony) Amelio recently began his joint appointment as assistant professor in the Department of Dental Ecology at the UNC School of Dentistry and as associate member at UNC Lineberger.
Sharon Campbell, professor of biochemistry and biophysics, has been awarded the 2014 Hyman L. Battle Distinguished Cancer Research Award by the UNC School of Medicine. The award recognizes sustained, exceptional cancer research over a career by School of Medicine faculty.
The Bladder Cancer Advocacy Network (BCAN) has awarded William Kim, MD, associate professor of medicine, urology, and genetics, University of North Carolina at Chapel Hill and UNC Lineberger Comprehensive Cancer Center, with the 2014 Bladder Cancer Research Innovation Award to support his project “Immune Characterization of High-Grade Bladder Cancer.”
Six UNC Lineberger members are among the most often-cited scientists in the world, according to the Thomson Reuters 2014 Highly Cited Researchers list.
Cancer care in North Carolina is the focus of the July/August issue of the North Carolina Medical Journal (NCMJ). The issue, co-guest-edited by UNC Lineberger Comprehensive Cancer Center members Ethan Basch, MD, and Stephanie Wheeler, PhD, MPH, features articles on a wide variety of issues that determine how the state’s residents receive treatment for cancer.
Obesity, epidemic in the U.S. and worldwide, is one of the important modifiable risk factors for breast cancer, especially a particularly aggressive subtype called basal-like breast cancer (BBC). Population studies have suggested that lifestyle interventions, including weight loss, could prevent a large proportion of this type of cancer; however, data on the effect of weight loss on BBC risk are limited and the mechanisms involved uncertain.
Though cancer screening has come a long way, physicians still do not thoroughly discuss with patients the advantages and disadvantages of these procedures before decisions are made to undergo the screenings, according to a new study co-authored by a physician from The University of North Carolina at Chapel Hill’s Gillings School of Global Public Health.
The ability of researchers and physicians to use DNA sequencing to pinpoint the genetic mutations that cause cancer has led to greater understanding of the causes of the disease and development of drugs that treat tumors by targeting specific mutations. A pair of papers published by researchers at the UNC Lineberger Comprehensive Cancer Center reveal new tools that can improve the accuracy of tumor sequencing.