UNC Lineberger News

Kinase test may yield big gains for drug-resistant cancers

Chapel Hill, NC – In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases “en masse”, enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies.

Kinase test may yield big gains for drug-resistant cancers - Read More…

Gene switches do more than flip “on” or “off”

Gene switches do more than flip “on” or “off”

Chapel Hill - Anyone who’s tried a weekend home improvement project knows that to do a job right, you’ve got to have the right tools. For cells, these “tools” are proteins encoded by genes.

Gene switches do more than flip “on” or “off” - Read More…

Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting

Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting

Nancy DeMore, MD, and colleagues presented an abstract at the recent Society of Surgical Oncology 65th annual cancer symposium held in Orlando, Florida in March. Dr. DeMore is an associate professor of surgery and a member of UNC Lineberger.

Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting - Read More…

UNC’s Neuro-oncology program recognizes Ependymoma Awareness Day on April 19th

UNC’s Neuro-oncology program recognizes Ependymoma Awareness Day on April 19th

UNC Cancer Care’s neuro-oncology program will recognize Ependymoma Awareness Day on April 19th, as part of the program’s overall efforts to increase public awareness of this rare tumor and the need for clinical studies to improve early diagnosis, standardize treatment and improve the health status of those living with this disease.

UNC’s Neuro-oncology program recognizes Ependymoma Awareness Day on April 19th - Read More…

Evans quoted in The News & Observer, Scientific American Blog

Evans quoted in The News & Observer, Scientific American Blog

James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, is quoted in recent articles in The News & Observer and the Scientific American blog.

Evans quoted in The News & Observer, Scientific American Blog - Read More…

Clinical trial of experimental drug targeting mutation in thyroid cancer shows clinical benefit

Clinical trial of experimental drug targeting mutation in thyroid cancer shows clinical benefit

Chapel Hill - In a clinical trial of an experimental drug to treat thyroid cancer, UNC and six other institutions report the first evidence in this tumor that targeting therapy to an oncogene documented to be present in the patient receiving therapy may be associated with clinical benefit.

Clinical trial of experimental drug targeting mutation in thyroid cancer shows clinical benefit - Read More…

Sharpless, Zanation honored as Health Care Heroes

Sharpless, Zanation honored as Health Care Heroes

UNC Lineberger faculty members Ned Sharpless, MD, and Adam Zanation, MD, were honored for their achievements by Triangle Business Journal as 2012 Health Care Heroes.

Sharpless, Zanation honored as Health Care Heroes - Read More…

Ollila, Burkhart talk about teenage tanning bed use

Ollila, Burkhart talk about teenage tanning bed use

David Ollila, MD, and Craig Burkhart, MD, spoke about teenage tanning bed use at a Child Fatality Task Force committee meeting on March 26, 2012. They discussed the option of banning teenagers below the age of 18 from tanning bed use.

Ollila, Burkhart talk about teenage tanning bed use - Read More…

UNC Lineberger scientist receives grant for pancreatic cancer research

UNC Lineberger scientist receives grant for pancreatic cancer research

The Lustgarten Foundation, the nation’s largest foundation dedicated solely to funding pancreatic cancer research, has awarded Channing Der, PhD, a $1.165 million grant to identify promising drug combinations for potential future use in clinical trials.

UNC Lineberger scientist receives grant for pancreatic cancer research - Read More…

Aspirin use may offer cancer prevention benefits, Baron dicusses on MedPage Today

Aspirin use may offer cancer prevention benefits, Baron dicusses on MedPage Today

John Baron, MD, was interviewed by Charles Bankhead of MedPage Today on March 21, 2012 to give his perspective on three recently published reviews in "The Lancet" and "The Lancet Oncology." The reviews suggest that "regular aspirin use leads to significant reductions in the risk of cancer, metastasis, and cancer mortality."

Aspirin use may offer cancer prevention benefits, Baron dicusses on MedPage Today - Read More…

Predictive biomarkers for lung cancer reported in laboratory finding

Predictive biomarkers for lung cancer reported in laboratory finding

A team of scientists, including several from UNC Lineberger, has identified predictive genetic biomarkers in pre-clinical models that affect response to therapy for non-small cell lung cancer (NSCLC). The study was done in parallel to an ongoing clinical trial among lung cancer patients at multiple institutions.

Predictive biomarkers for lung cancer reported in laboratory finding - Read More…

Lung cancer highlights from 2011, Weiss provides insight

Lung cancer highlights from 2011, Weiss provides insight

Jared Weiss, MD, gave a podcast titled "2011 Highlights in Lung Cancer" that was posted on cancergrace.org on March 15, 2012. In the podcast, Dr. Weiss talks about highlights in lung cancer from 2011 and also answers questions.

Lung cancer highlights from 2011, Weiss provides insight - Read More…

Joseph Pagano: still going “80 mph”

Joseph Pagano: still going “80 mph”

Internationally renowned virologist; past president of national cancer and international virology associations; National Academy of Science Institute of Medicine member; North Carolina Award for Science winner; revered mentor to faculty, fellows, medical and graduate students; Berryhill Lecturer; proud grandfather; dedicated squash and tennis player; and recent honoree at his eightieth birthday.

Joseph Pagano: still going “80 mph” - Read More…

real doctors, real people - N.E.D.

real doctors, real people - N.E.D.

N.E.D. is a rock band. The members of the band are gynecologic cancer surgeons from all over the country and two of them, Dr. John Boggess and Dr. John Soper, work here at UNC Health Care.

real doctors, real people - N.E.D. - Read More…

UNC researchers: Benefits of varenicline (Chantix) may balance certain risks

Drs. Christine E. Kistler and Adam Goldstein discuss how clinicians can better have conversations about the balance between short-term risk of adverse cardiovascular events associated with taking Chantix compared to the long-term reduction in the risk of death that results from smoking cessation.

UNC researchers: Benefits of varenicline (Chantix) may balance certain risks - Read More…

Hiding emotions may exacerbate depression among black men who confront racial discrimination

Hiding emotions may exacerbate depression among black men who confront racial discrimination

Enduring subtle, insidious acts of racial discrimination is enough to depress anyone, but African-American men who believe that they should respond to stress with stoicism and emotional control experience more depression symptoms, according to new findings from the University of North Carolina at Chapel Hill.

Hiding emotions may exacerbate depression among black men who confront racial discrimination - Read More…

UNC study identifies pockets of high cervical cancer rates in North Carolina

A study of cervical cancer incidence and mortality in North Carolina has revealed areas where rates are unusually high.

UNC study identifies pockets of high cervical cancer rates in North Carolina - Read More…

UNC research center receives contract to fight kidney cancer

UNC research center receives contract to fight kidney cancer

The Center for Integrative Chemical Biology and Drug Discovery at the University of North Carolina at Chapel Hill has received a contract from SAIC-Frederick, Inc. to develop potential drug leads for treating renal cell carcinoma, the most common type of kidney cancer in adults.

UNC research center receives contract to fight kidney cancer - Read More…

Small DNA circles found outside the chromosomes in mammalian cells and tissues, including human cells

Small DNA circles found outside the chromosomes in mammalian cells and tissues, including human cells

CHAPEL HILL, N.C. – Researchers from the University of North Carolina at Chapel Hill have helped identify a new DNA entity in mammalian cells and provided evidence that their generation leaves behind deletions in different locations of the cells’ genetic program, or genome.

Small DNA circles found outside the chromosomes in mammalian cells and tissues, including human cells - Read More…

Gershon receives grant to study brain tumor, develop novel therapy

Gershon receives grant to study brain tumor, develop novel therapy

Timothy Gershon, MD, PhD, assistant professor of neurology, has received a four-year National Institutes of Health Mentored Clinical Scientist Research Career Development Award grant from the National Institute of Neurologic Disease and Stroke.

Gershon receives grant to study brain tumor, develop novel therapy - Read More…

Tobacco companies, convenience stores form 'deadly alliance' to entice kids to smoke, report says

Tobacco companies, convenience stores form 'deadly alliance' to entice kids to smoke, report says

Tobacco companies have enlisted convenience stores as their most important partners in marketing tobacco products and fighting policies that reduce tobacco use, according to a report released today by leading public health organizations, including The University of North Carolina Gillings School of Global Public Health.

Tobacco companies, convenience stores form 'deadly alliance' to entice kids to smoke, report says - Read More…

Drug helps purge hidden HIV virus, study shows

Drug helps purge hidden HIV virus, study shows

CHAPEL HILL -- A team of researchers at the University of North Carolina at Chapel Hill have successfully flushed latent HIV infection from hiding, with a drug used to treat certain types of lymphoma.

Drug helps purge hidden HIV virus, study shows - Read More…

Wallen named 2012 American Urological Association Teacher of the Year

Wallen named 2012 American Urological Association Teacher of the Year

This award, initiated by the AUA Residents Committee and approved by the AUA Board, is presented annually to recognize an outstanding urology educator or program director who has dedicated a portion of his/her career to teaching residents and advancing urology graduate medical education.

Wallen named 2012 American Urological Association Teacher of the Year - Read More…

Muss, Keith talk about cancer care and families

Muss, Keith talk about cancer care and families

Loretta Muss, Coordinator of the N.C. Cancer Hospital Patient and Family Advisory Board, and fellow board member, Ryan Keith, talked about cancer care & families on the February 25, 26, and 27 broadcasts of YOUR HEALTH®.

Muss, Keith talk about cancer care and families - Read More…

Protein complex affects cells’ ability to move, respond to external cues

Protein complex affects cells’ ability to move, respond to external cues

Chapel Hill, NC – In a paper published today in the journal, Cell, a team from the University of North Carolina at Chapel Hill has explained for the first time how a long-studied protein complex affects cell migration and how external cues affect cell’s ability to migrate.

Protein complex affects cells’ ability to move, respond to external cues - Read More…

Testicular cancer treatment, one patient's story

UNC Lineberger patient David Alston talks about the treatment he is undergoing for testicular cancer.

Testicular cancer treatment, one patient's story - Read More…

Men share emotional support through written messages

The story "Men find emotional support on hospital bathroom's dry erase board" aired on February 23, 2012 on WRAL.

Men share emotional support through written messages - Read More…

Managing the impact of drug shortages

The story "Shortages Of Life-Saving Drugs Getting Worse" aired today on WFAE 90.7, Charlotte's NPR news source.

Managing the impact of drug shortages - Read More…

First Cancer Transitions Workshop a success

First Cancer Transitions Workshop a success

UNC Lineberger’s Carolina Well and the Comprehensive Cancer Support Program (CCSP) offered a workshop on “Cancer Transitions: Promoting Wellness & Group Process” for community outreach coordinators and their community partners as well for interested UNC nurses and staff.

First Cancer Transitions Workshop a success - Read More…

North Carolina-based genetic resources fuel big scientific progress

Chapel Hill, NC – A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross – a “library” of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.

North Carolina-based genetic resources fuel big scientific progress - Read More…

UNC Curriculum in Genetics and Molecular Biology rated among the very best

Training the next generation of scientists is vital to continued progress in understanding cancer and all human disease. But how do students evaluate the programs offered by colleges and universities to decide which program is the best fit for them?

UNC Curriculum in Genetics and Molecular Biology rated among the very best - Read More…

Weighing the difference: switching to water, diet beverages can tip the scales

Weighing the difference: switching to water, diet beverages can tip the scales

Making a simple substitution of water or diet soft drinks for drinks with calories can help people lose four to five pounds, a new University of North Carolina at Chapel Hill study shows.

Weighing the difference: switching to water, diet beverages can tip the scales - Read More…

UNC scientists publish results from breast cancer survivors wellness workshops

Scientists from UNC Lineberger have published a report describing an outreach program they developed for breast cancer survivors in four NC counties.

UNC scientists publish results from breast cancer survivors wellness workshops - Read More…

Marks talks about newest radiation treatment and what it offers

Marks talks about newest radiation treatment and what it offers

Lawrence Marks, MD, chair of UNC's department of radiation oncology and a UNC Lineberger member, is quoted in the article "TomoTherapy offers safer radiation" published in today's issue of The News & Observer.

Marks talks about newest radiation treatment and what it offers - Read More…

N.C. Cancer Hospital on “Great Oncology Program” list

Becker's Hospital Review has named the N.C Cancer Hospital as one of "70 Hospitals with Great Oncology Programs."

N.C. Cancer Hospital on “Great Oncology Program” list - Read More…

Triangle Bladder Cancer Support Group: Here to Help

Triangle Bladder Cancer Support Group: Here to Help

Bladder cancer patients in the Triangle area are not alone. They have a monthly group where “true loving support for each other” is shared, says David Langham, a bladder cancer survivor and one of the organizers of the group.

Triangle Bladder Cancer Support Group: Here to Help - Read More…

UNC and partners to study policies to restrict tobacco marketing at point of sale: multi-institutional $6.7 million research grant awarded

UNC and partners to study policies to restrict tobacco marketing at point of sale: multi-institutional $6.7 million research grant awarded

The way tobacco products are marketed and sold changed with the June 2009 passage of the Family Smoking Prevention and Tobacco Control Act. For example, this law mandates larger and stronger warning labels on packs and advertising and prohibits the sale of “light” and clove cigarettes. The FDA Act also now allows states and local communities to regulate the time, place, and manner of tobacco advertising. Thus, states could restrict tobacco promotions or restrict the location of tobacco advertising.

UNC and partners to study policies to restrict tobacco marketing at point of sale: multi-institutional $6.7 million research grant awarded - Read More…

UNC scientists collaborate on colon cancer therapy comparative effectiveness study

UNC scientists collaborate on colon cancer therapy comparative effectiveness study

In 2008 UNC and Harvard University’s Brigham and Women’s Hospital in Boston were selected by the U.S. Agency for Healthcare Research and Quality to carry out accelerated practical studies examining the comparative effectiveness of cancer treatments. The collaboration is called the Cancer Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Comparative Effectiveness Consortium.

UNC scientists collaborate on colon cancer therapy comparative effectiveness study - Read More…

Latest in treatment for Hodgkin Lymphoma, Park comments at annual ASH meeting

As part of Patient Power® coverage of the annual meeting of the American Society of Hematology (ASH), UNC Lineberger member Steven Park, MD, talks about the latest in treatment for Hodgkin Lymphoma.

Latest in treatment for Hodgkin Lymphoma, Park comments at annual ASH meeting - Read More…

real doctors, real people - Paul Godley

Whether photographing a child in the streets of Vietnam or consulting with a patient about a diagnosis, Dr. Paul Godley employs his intuition and charming personality to put the person in front of him at ease within a matter of moments.

real doctors, real people - Paul Godley - Read More…

UNC scientists collaborate to find first major genetic mutation associated with hereditary prostate cancer risk

UNC scientists collaborate to find first major genetic mutation associated with hereditary prostate cancer risk

Chapel Hill - After a 20-year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the disease.

UNC scientists collaborate to find first major genetic mutation associated with hereditary prostate cancer risk - Read More…

UNC radiation oncologists co-author Journal of Clinical Oncology editorial on breast cancer radiotherapy and coronary artery stenosis

UNC radiation oncologists co-author Journal of Clinical Oncology editorial on breast cancer radiotherapy and coronary artery stenosis

Timothy Zagar, MD, assistant professor of radiation oncology, and Lawrence Marks, MD, professor and chair of radiation oncology, co-authored an editorial in the December 27, 2011 issue of the Journal of Clinical Oncology.

UNC radiation oncologists co-author Journal of Clinical Oncology editorial on breast cancer radiotherapy and coronary artery stenosis - Read More…