- Molecular Therapeutics
- Research Associate Professor
- UNC-Chapel Hill
- 1310 Kerr Hall Chapel Hill, NC 27599
Area of Interest
I joined the UNC-Chapel Hill Eshelman School of Pharmacy, the Division of Molecular Pharmaceutics, on July 2005, working as a Research Associate Professor. Before arriving in Chapel Hill, my research focused on developing nonviral vectors for gene delivery. As a first author, I published the hydrodynamic method, a platform which has been used worldwide in the field of gene therapy and has been cited 898 times. I also reported for the first time that efficient gene transfer to the lung requires a high charge ratio of cationic lipid to DNA. In addition, I developed a non-immunostimulatory nonviral vector which encapsulates small molecules to specifically inhibit the NF-B and the MAPK inflammatory pathway.