A recent U.S. News & World Report article highlights the nation’s cancer centers, focusing especially on those that the National Cancer Institute has designated as comprehensive cancer centers, citing advantages of patients being seen at or referred to these sites, including advances in technology and collaboration.
Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill and other TCGA sites, not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development.
Jean B. Sellers, RN, MSN has co-authored a chapter in the newly published book, Oncology Nurse Navigation: Delivering Patient-Centered Care Across the Continuum.
Nicole Baker, graduate student in the Department of Pharmacology, and member of Channing Der's lab, is the recipient of an a National Institutes of Health National Research Service Award Pre-Doctoral Fellowship.
Faculty members at the University of North Carolina School of Dentistry, The Scripps Research Institute (TSRI) and other institutions have discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer’s underlying genetic causes.
Feng Liu, PhD, a research professor in the Division of Molecular Pharmaceutics and UNC Lineberger member, died tragically Thursday, July 24, after being assaulted and robbed while walking in a neighborhood near campus. Liu was a dedicated colleague, educator and researcher focused on gene and drug delivery.
Hepatitis C virus (HCV) lingers in the human body for years, slowly damaging the liver and leading to liver diseases such as hepatitis, cirrhosis and liver cancer, which is often fatal. Research conducted at the University of North Carolina at Chapel Hill has discovered a mechanism that facilitates the virus achieving this life-long persistence. Chronic HCV infection is the leading cause of liver cancer in the United States.
UNC Hospitals is nationally ranked in cancer, taking the number 38th spot in the country. The latest ranking is up from 43rd in 2013.
Dr. Antonio (Tony) Amelio recently began his joint appointment as assistant professor in the Department of Dental Ecology at the UNC School of Dentistry and as associate member at UNC Lineberger.
William K. Kaufmann, PhD, article on chromosomal mutations in melanoma has been chosen as the featured Editor’s Choice article in the journal Environmental and Molecular Mutagenesis. The paper, which will be featured on the issue’s cover, was chosen because of the potential of the research to lead to new treatment approaches for melanoma.
Terence Wong, MD, PhD, Director of Molecular Imaging and Medical Director of the Biomedical Research Imaging Center (BRIC), will serve as a representative on the National Cancer Institute’s Gastrointestinal Steering Committee, formed to improve clinical trials in gastrointestinal cancer clinical research. Dr. Wong will represent the ECOG-ACRIN Cancer Research Group, a clinical trial cooperative group.
Hyman Muss, MD, director of the Geriatric Oncology Program at UNC Lineberger, published a Grand Rounds article on adjuvant chemotherapy for older women with breast cancer in the Journal of Clinical Oncology.
The Cancer Genome Atlas has published a comprehensive genomic profile of the cancer lung adenocarcinoma, one of the leading causes of death worldwide, in the journal Nature. Members contributing to the paper include Neil Hayes, Matthew Wilkerson, Katherine Hoadley, Charles Perou, Joel Parker, Mei Huang, Kimryn Rathmell and others.
Jennifer Webster-Cyriaque, DDS, PhD, will serve as a member of the National Institutes of Health’s Cancer Etiology Study Section, Center for Scientific Review. Members are selected on the basis of their demonstrated competence and achievement in their scientific discipline as evidenced by the quality of research accomplishments, publications in scientific journals, and other significant scientific activities, achievements and honors. The appointment will last until 2020.
Sharon Campbell, professor of biochemistry and biophysics, has been awarded the 2014 Hyman L. Battle Distinguished Cancer Research Award by the UNC School of Medicine. The award recognizes sustained, exceptional cancer research over a career by School of Medicine faculty.
Katie Reeder-Hayes, MD, and Lisa A. Carey, MD, have published an editorial in the Journal of Clinical Oncology titled "How Low Should We Go? The Search for Balance in Management of Small Human Epidermal Growth Factor Receptor 2–Positive Breast Cancers." The editorial accompanies an article analyzing the outcomes among women with small, node-negative, HER2-positive tumors.
The Bladder Cancer Advocacy Network (BCAN) has awarded William Kim, MD, associate professor of medicine, urology, and genetics, University of North Carolina at Chapel Hill and UNC Lineberger Comprehensive Cancer Center, with the 2014 Bladder Cancer Research Innovation Award to support his project “Immune Characterization of High-Grade Bladder Cancer.”
Six UNC Lineberger members are among the most often-cited scientists in the world, according to the Thomson Reuters 2014 Highly Cited Researchers list.
Cancer care in North Carolina is the focus of the July/August issue of the North Carolina Medical Journal (NCMJ). The issue, co-guest-edited by UNC Lineberger Comprehensive Cancer Center members Ethan Basch, MD, and Stephanie Wheeler, PhD, MPH, features articles on a wide variety of issues that determine how the state’s residents receive treatment for cancer.
Obesity, epidemic in the U.S. and worldwide, is one of the important modifiable risk factors for breast cancer, especially a particularly aggressive subtype called basal-like breast cancer (BBC). Population studies have suggested that lifestyle interventions, including weight loss, could prevent a large proportion of this type of cancer; however, data on the effect of weight loss on BBC risk are limited and the mechanisms involved uncertain.