In partnership with clinical investigators in gynecologic oncology, the UNC Health Registry/Cancer Survivorship Cohort (HR/CSC) provided recruitment, data collection through patient interviews, and support for multiple publications.
After weighing the risk of serious side effects with the benefits of a breast cancer prevention drug, a study led by a University of North Carolina at Chapel Hill researcher found that the drug’s benefits outweighed risks for most, but not all women.
Andrew Zhuang Wang, MD, of the UNC Lineberger Department of Radiation Oncology, was published in the journal Nanoscale. The paper, "Nanoparticle delivery of chemosensitizers improve chemotherapy efficacy without incurring additional toxicity," was accepted by the journal Jan. 4. Wang and other researchers demonstrated proof of the principle of using a nanoparticle formulation for drugs that improve the sensitivity of tumors to chemotherapy.
Eight year old Emily McCann of Apex came to the N.C. Cancer Hospital at the end of December bearing gifts. She brought money to help meet the needs of pediatric cancer patients, but she also brought cheer, comfort and hope.
Most cancer patients jump up and down after finishing therapy, but Richard Westin did much more. He jumped out of an airplane on a skydive to celebrate completing his chemo and radiation therapies and now jumps into water taking scuba diving lessons.
When Katy Sims enters the first-year class at the UNC School of Medicine this fall, she will already have extensive medical experience. Her decision to become a doctor came as she was undergoing treatment for Ewing sarcoma, a type of childhood cancer.
In early 2013, while pursuing a doctoral degree in theological anthropology at Trinity College in Dublin, Ireland, Lynn Latchford began to experience some puzzling symptoms. Routine academic tasks suddenly became difficult. Mental fogginess was accompanied by fatigue, weight gain and changes in her sense of smell, taste and hearing. Doctors attributed her symptoms to a chronic thyroid disorder and stress.
Daniel Fischler remembers the call. “When a doctor calls you at 10:30 on a Friday night, it’s not going to be good news.” He had undergone an MRI for a herniated disc, but when the test revealed a shadow on his left bowel, a CT was ordered. Then came the call from his doctor. “He told me that it was very likely a tumor. I was knocked out, shocked by the bad news.”
In 2011, Tricia Prestia was wearing a lot of hats. A wife, a mother and a busy women’s health nurse practitioner in Cary, Tricia drew on her training and experience as a cytologist - the person who studies cellular changes that may indicate cancer - in her nursing practice.
Eight years after her diagnosis, lung cancer survivor Tomma Hargraves is training to become a lay navigator with UNC Lineberger, giving back to the hospital that she credits with saving her life.
Leading an active life can help women treated for breast cancer live longer and healthier lives. Just ask Sherdinia Thompson-Dunn of Carrboro, NC. Thompson-Dunn, a 1967 graduate of UNC, found some pleasant surprises when she began a self-directed walking program in October 2013 following treatment for breast cancer.
Researchers look at area around tumors to help personalize treatment for triple-negative breast cancer
The Duke Endowment awards $461,750 grant to UNC Lineberger’s Comprehensive Cancer Support Program.
Temitope Keku, MSPH, PhD has published a review in The American Journal of Physiology—Gastrointestinal and Liver Physiology titled “The Gastrointestinal Microbiota and Colorectal Cancer.” Coauthors include Drs. Santosh Dulal, April Deveaux, Biljana Jovov, and Xuesong Han. This article provides an overview on the role of resident gut microbiota in the development of human colorectal cancer and explores its association with diet and inflammation.
Ebix, Inc., today announced that the annual Ebix Charity Challenge, will be held in Greensboro, North Carolina on February 7, 2015. All proceeds from the 5th Annual Ebix Charity Challenge will benefit the UNC Lineberger Comprehensive Cancer Center, where America No. 1 John Isner’s mother, Karen, was successfully treated during her two battles with colon cancer.
UNC Lineberger members Joseph DeSimone, PhD and Jenny Ting, PhD, along with other researchers at the UNC-Chapel Hill and North Carolina State University have uncovered a novel approach to creating inhalable vaccines using nanoparticles that shows promise for targeting lung-specific diseases, such as influenza, pneumonia and tuberculosis. The findings, published in the Proceedings of the National Academy of Sciences, also have broad public health implications for improving the accessibility of vaccines.
Researchers at the UNC-Chapel Hill and North Carolina State University have uncovered a novel approach to creating inhalable vaccines using nanoparticles that shows promise for targeting lung-specific diseases, such as influenza, pneumonia and tuberculosis. The work was led by Cathy Fromen and Gregory Robbins, members of the DeSimone and Ting labs at UNC Lineberger, and reveals that a particle’s surface charge plays a key role in eliciting immune responses in the lung.
Carolina legend Danny Talbott performed at the highest level on both the football field and baseball diamond during his years as a Tar Heel. Since 2010, he’s been back in Chapel Hill, battling the toughest opponent he’s faced: multiple myeloma. He can’t imagine going anywhere else to do it.
2014 was an exciting year for UNC Lineberger. Check out this graphic that shows what amazing progress you helped us make over the last 12 months - by the numbers.
UNC Lineberger Comprehensive Cancer Center member Jim Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine and director of clinical cancer genetics, has co-authored a commentary on proposed US Food and Drug Administration (FDA) regulation of genetic testing in the Journal of the American Medical Association (JAMA).