Recent News

Blood cancer treatment may age immune cells as much as 30 years

Blood cancer treatment may age immune cells as much as 30 years

Researchers led by UNC Lineberger Director Norman Sharpless, MD, and William Wood, MD, uncovered clues that suggest that stem cell transplant is linked to a marked increase in the “molecular age” of these immune cells in a group of patients with blood cancer.

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Researchers question process for reviewing coverage of ‘off label’ cancer drug use

Researchers question process for reviewing coverage of ‘off label’ cancer drug use

In a paper published online by the Journal of the American Medical Association, UNC Lineberger physician-researchers led by Ethan Basch, MD, MSc, raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which drugs it will reimburse for off-label uses in cancer care.

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Study finds links between physicians setting cancer care guidelines and drug industry

Study finds links between physicians setting cancer care guidelines and drug industry

UNC Lineberger researchers, led by Aaron Mitchell, MD, found a high prevalence of financial relationships among authors who helped develop a leading set of cancer care guidelines in the United States in a study published in JAMA Oncology. They say the work lays the foundation for future studies of whether the payments influenced clinical practice or guideline recommendations.

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Researchers use genetics to probe immune system’s role in fighting cancer

Researchers use genetics to probe immune system’s role in fighting cancer

Findings published in the Journal of the National Cancer Institute show that immune cells do not respond the same way to all tumor types. The study, led by UNC Lineberger researcher Benjamin Vincent, MD, could lay the foundation for the discovery of biomarkers to determine which patients might respond to certain immune-stimulating cancer treatments.

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