New test uses PAM50 breast cancer gene signature discovered by UNC’s Perou
Post-doctoral fellows Scott Rothbart, PhD; Gidi Shemer, PhD; and Angela Wahl, PhD, are the recipients of the Joseph S. Pagano Award for a paper by a postdoctoral fellow published in 2012.
Physicians experience increased effort and uncertainty in cross-coverage of radiation oncology patients
Radiation oncology physicians who encounter an unfamiliar case when cross covering for another physician experience higher levels of perceived workload and may perhaps also effects on performance, according to research conducted at the University of North Carolina.
Prostate cancer treatment delays onset of pain and quality of life deterioration in men with metastatic prostate cancer
Abiraterone acetate, a recently FDA-approved drug used to treat men with metastatic castration-resistant prostate cancer, significantly delays progression of pain and quality of life deterioration when taken in conjunction with prednisone.
The national Pink Heals Tour visited UNC on Friday, September 20 with a fleet of pink fire trucks, a bus and emergency vehicles. Chapel Hill Fire Department, the host for the visit, brought their Carolina Blue fire truck.
Dr. Cynthia Powell of N.C. Children's Hospital and Dr. Jonathan Berg of UNC Lineberger Comprehensive Cancer Center will answer your questions in a live Facebook chat at noon (12 p.m.) Eastern time on Thursday, Sept. 26.
An 82-year-old resident of Aurora, N.C., is referred to UNC Hospitals for treatment of a nasal cavity cancer in the post of tissue between his nostrils. A multidisciplinary treatment decision, the support of his family and a stay at SECU Family House see him through.
UNC and Wake Forest awarded FDA, NIH grant to create Center for Regulatory Research on Tobacco Communications
Although cigarette use has declined among Americans, regulators face the challenge of communicating the dangers of new tobacco products along with reaching smokers in diverse communities who may not respond to traditional forms of anti-tobacco communication. To address these issues, the U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) announced today that they are awarding a $19.4 million, five-year grant to fund a center at the University of North Carolina that will study issues related to tobacco prevention communication and regulation.
Governor Pat McCrory and First Lady Ann McCrory proclaimed September 13 as Childhood Cancer Awareness Day in North Carolina
The Honorable Pat McCrory Governor of the State of North Carolina, and First Lady Ann McCrory visited the North Carolina Children’s Hospital on September 13 to proclaim that day as Childhood Cancer Awareness Day in North Carolina.
Dr. Oliver Smithies won the Nobel Prize for his research in gene modification. What you may not know is that since he was a child, he's been enthralled with flying.
E. Claire Dees, MD, associate professor of medicine, and Peter Voorhees, MD, associate professor of medicine, have been appointed to leadership positions in UNC Lineberger Comprehensive Cancer Center. Dr. Dees will serve as medical director of the Clinical Protocol Office and Dr. Voorhees will serve as chair of the Protocol Review Committee.
Racial disparities in the treatment and outcome of breast cancer patients arise from a combination of biological, social and financial causes. Understanding how these complex factors influence interactions between patients and the medical community is key to reducing the gaps in treatment and mortality between racial groups, according to researchers at the University of North Carolina.
As the clinical use of genomic testing expands, the practical and ethical considerations of using the technology to screen newborns for genetic conditions will be the focus of a new study undertaken at the University of North Carolina.
As a clinical nurse IV in the outpatient clinics of N.C. Cancer Hospital, Collier plays many roles from nurse manager to caring for patients. He's used to playing different roles though as he's been into drama and theater about as long as he's been in nursing
Ethan Basch, MD, Director, Cancer Outcomes Research Program at UNC Lineberger, discussed incorporating measurements of patient well-being into developing new treatments with CancerNetwork writer Anna Azvolinsky in an Aug. 28, 2013 podcast.
Encouraging physicians to recommend human papillomavirus (HPV) vaccine to adolescent boys and their parents - and educating the boys and their families about the importance of receiving the vaccine - are essential to reducing the cancers this virus can cause.
David Ollila, MD, professor of surgery, has been appointed to the James H. and Jesse E. Millis Distinguished Professorship. The $1.5 million professorship was established by their son, William (Bill) Millis in honor of his parents, Jim and Jesse Millis of High Point, N.C.
The North Carolina Biotechnology Center awarded more than $460,000 in grants to support research and infrastructure needs of members of the UNC Lineberger Comprehensive Cancer Center researching cancer and cell biology.
An article in the New York Times Magazine profiled work by Barbara L. Fredrickson, Kenan Distinguished Professor of psychology in the College of Arts and Sciences, in partnership with Steven Cole, PhD, Professor of Medicine and Psychiatry and Biobehavioral Sciences in the University of California Los Angeles School of Medicine, into the genomic effects of happiness.
On August 20, 2013, UNC Lineberger held a reception to honor Charles M. “Chuck” Perou, PhD, for his 2013 Hyman L. Battle Distinguished Cancer Research Award.
Katy Jones has been hired as director of communications and marketing for the UNC Lineberger Comprehensive Cancer Center, effective August 19, 2013.
William Roper, MD, MPH, Dean of the School of Medicine, Vice Chancellor for Medical Affairs, and CEO of University of North Carolina Health Care System, announces the appointment of Norman "Ned" Sharpless, MD, as director of the University of North Carolina Lineberger Comprehensive Cancer Center, effective January 1, 2014.
UNC Lineberger scientists Blossom Damania, PhD, Dirk Dittmer, PhD, and Liza Makowski, PhD, have been awarded two-year National Cancer Institute Provocative Questions grants.
"Scientists say blueberries powerful antioxidants and anthocyanins make them one of nature's top cancer fighters, two things that hit home for North Carolina women's basketball coach Sylvia Hatchell."
A team of researchers has published their analysis of survival rates among study participants in the 2003 Prostate Cancer Prevention Trial showing that the prostate drug finasteride does not decrease survival after a diagnosis of prostate cancer. Their 2003 publication found that while the drug finasteride significantly reduced the risk of prostate cancer, it was associated with an increased risk of high-grade disease and possibly decreased survival.
Like a toddler in need of a nap or a snack, the cells of our bodies can turn a bit sour under conditions of stress or nutrient deprivation. The pH levels inside these cells – starved, perhaps by a heart attack or other injury – have been known to drop dramatically in a cry for help.
Researchers at the University of North Carolina and the National Institutes for Health have defined the role of the protein vinculin in enabling cell movement. In a paper published in the Journal of Cell Biology, Sharon Campbell, PhD, professor of Biochemistry and Biophysics and member of UNC Lineberger Comprehensive Cancer Center, and Clare Waterman of the National Heart, Lung and Blood Institute at the National Institutes of Health showed that cell mobility occurs through the interactions between the protein vinculin and the cytoskeletal lattice formed by the protein actin. By physically binding to the actin that makes up the cytoskeleton, vinculin operates as a form of molecular clutch transferring force and controlling cell motion.
A rapidly-dissolvable microneedle patch developed by a UNC team led by Joseph DeSimone, William R. Kenan, Jr. Distinguished Professor of Chemistry and Chemical Engineering, and director of the UNC Institute for Advanced Materials, Nanoscience, and Technology and member of UNC Lineberger, allows for painless injections of medicine and vaccines.
Bob Goldstein, PhD, professor of biology, talks about his career and the promise of cell biology in a profile in the August issue of The Journal of Cell Biology.
Human bodies recognize at the molecular level that not all happiness is created equal, responding in ways that can help or hinder physical health, according to new research led by Barbara L. Fredrickson, Kenan Distinguished Professor of psychology in the College of Arts and Sciences at the University of North Carolina at Chapel Hill.
Since 2011, the University of North Carolina has partnered with the government of Malawi to establish a pathology laboratory in the nation’s capital, building on an existing decades-long collaboration. The laboratory has provided an invaluable service to patients and has also built capacity at a national teaching hospital, according to an analysis of the first 20 months of operation published August 7 online by PLOS ONE.
UNC Gazette - Oliver Smithies and Nobuyo Maeda were born in island countries half a world apart – he in England, she in Japan – but each in their own way found a path to a life in science.
Susan G. Komen for the Cure has awarded more than $800,000 to researchers with the UNC Lineberger Comprehensive Cancer Center to fund research into fighting cancer.
The tyrosine kinase MerTK plays a prominent role in the body’s immune response. MerTK signaling helps “calm” the body’s first line of immunity, the macrophage, while it performs the routine duties - clearing cells that die and healing damaged tissue.
Brian Burnham is an assistant scout master and one of the leaders of Troop 845's Lucky 13 Bike Trip, a fundraiser for UNC Lineberger.
Research that developed a method of visualizing aging and tumor growth in mice by Norman Sharpless, MD, Wellcome Distinguished Professor of Cancer Research and Deputy Cancer Center Director, was featured in an article on biological markers of aging in the New York Times.
UCRF Competitive Grants Program 2013 Innovation Awards were chosen from 51 applications. The awards provided $1,180,000 to support research among the six winners.
WRAL features Bill McCulloch, known as Windy City Slim, a blues singer who learned to reclaim his voice after treatment from head and neck cancer caused his vocal muscles to atrophy.
The National Institute of Health has awarded University of North Carolina researcher Lishan Su, PhD, with a $2 million four-year R01 grant to investigate using a novel immune therapy to treat chronic hepatitis B virus (HBV) infection.
Jahan Mohiuddin developed a tool to determine a patient’s risk of breast cancer relapse.
Albert Baldwin, PhD, Professor of Biology and Associate Director of Basic Research at UNC Lineberger discusses the regulation and biological functions of NF-κB in cancer at OncLive.
A 65-year-old Person County man is successfully treated for a rare head and neck cancer, but the treatment side effects damaged his teeth and gums. He may have lost his pearly whites, but not his spirit or his faith.
Shellie Ellis, MA, and Shelley Golden, PhD, of the Gillings School of Global Public Health are the 2013 recipients of the Marci Kramish Campbell Dissertation Award, a competitive $5,000 award to recognize excellence in dissertation research focused on cancer and the population sciences.
RNA Diagnostic Test from Paraffin Improves Lung Cancer Diagnosis Over Routine Microscopic Evaluation Alone
Knowing what type of lung cancer a patient has is critical to determine which drug will work best and which therapies are safest in the era of personalized medicine. Key to making that judgment is an adequate tumor specimen for the pathologist to determine the tumor’s histology, a molecular description of a tumor based on the appearance of cells under a microscope. But not all specimens are perfect, and are sometimes so complex that a definitive diagnosis presents a challenge.
Stephanie Wheeler, PhD, assistant professor of health policy and management at Gillings School of Global Public Health, will receive $727,000 over five years through an American Cancer Society Mentored Research Scholar Grant.
National quality assessment programs usually measure and reward practices based on improving clinical processes such as re-hospitalization or infection rates. While this type of information is important and useful to clinicians, it doesn’t always take into account what is most important to the patient and families of the patient receiving care, such as the management of long-term symptoms or ability to conduct daily activities.
For decades, women between the ages of 21 and 69 were advised to get annual screening exams for cervical cancer. In 2009, however, accumulating scientific evidence led major guideline groups to agree on a new recommendation that women be screened less frequently: every three years rather than annually.
Different factors influence delay between diagnosis and first course of treatment for breast cancer for African-American and White women.
UNC has lost a dear colleague. Dr. Keith Amos died suddenly in Edinburgh, Scotland, while on a Dr. Claude Organ, Jr., Travel Award from the American College of Surgeons. We all hold in our thoughts his wife, Ahaji, and their three young daughters.
Albert Baldwin, PhD, William Rand Kenan Professor of Biology and associate director of UNC Lineberger Comprehensive Cancer Center, has received a one-year continuation grant from the Samuel Waxman Cancer Research Foundation.