Featured Clinical Trials

The UNC Brain Metastasis Specialty Clinic seeks to offer a portfolio of clinical trials. Some of our most exciting trials are featured below.

CT Through WindowAn open-label, Phase I/IIa, dose escalating study of 2B3-101 in patients with solid tumors and brain metastases or recurrent malignant glioma.

PI: Carey Anders, MD

Contact: Rachel Phipps, RN. Telephone (919) 843-7197 or or toll free 1-877-668-0683. .

N107C:  A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease. 

PI:  Timothy Zagar, MD

Contact: Becky Lynch.  Telephone (919) 843-7112.

RTOG0933:  A Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases

PI:  Timothy Zagar, MD

Contact: Lori Stravers.  Telephone: (919) 445-5242 or toll free 1-877-668-0683.

PI: Claire Dees, MD

Contact: Rachel Phipps, RN. Telephone (919) 843-7197 or or toll free 1-877-668-0683. .

LCCC1025:  A Phase II Study Evaluating The Efficacy And Tolerability Of Everolimus (RAD001) In Combination With Trastuzumab And Vinorelbine In The Treatment Of Progressive HER2-Positive Breast Cancer Brain Metastases

PI:  Carey Anders, MD

Contact:  Donna Rowe, RN.  Telephone (919) 966-7359 or toll free 1-877-668-0683. 

DFCI 10-107 Prospective Study of Neurocognitive Outcomes following Whole Brain Radiotherapy for Newly Diagnosed Brain Metastasis in Breast Cancer Patients.

PI:  Carey Anders, MD

Contact: Sonali Rege.  Telephone (919) 966-4432 or toll free 1-877-668-0683. 

Search all UNC Lineberger Clinical Trials