School of Medicine
Area of interest
My research interest is somatic mutation testing in cancer. Somatic mutations are indicators of which pathways have been altered in cancer cells. Numerous therapies and clinical trials are selected for use in patients based on these changes.
My primary research role is to provide anatomic and molecular pathology support for the UNCseq (LCCC1108) project, which identifies clinically actionable somatic mutations in cancer patients using massively parallel sequencing. In addition, I oversee the germline genetic analysis of these patients in order to identify hereditary mutations that result in clinically relevant syndromes. Clinically, I oversee the development of somatic mutation testing panels using next generation sequencing in order to allow for more rapid analysis of mutations that are standard of care in patient treatment.