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Specialized Program of Research Excellence (SPORE) in Breast Cancer

One of only 11 Breast Cancer SPORE programs in the country, the NCI designation recognizes UNC Breast Care for its efforts to promote collaborative, interdisciplinary translational cancer research.

Researchers, clinicians and public health specialists at UNC and UNC Lineberger are working diligently to find new ways of detecting, treating and preventing breast cancer. Their work begins with the National Cancer Institute-funded Specialized Program of Research Excellence (SPORE) in Breast Cancer, one of eleven in the country.

Originally funded in 1992, the UNC SPORE in Breast Cancer has created an outstanding program in translational research. Its current five projects are conceptually linked by studies of breast cancer molecular phenotypes, particularly those with the worst prognosis: basal-like tumors, luminal B tumors, and tumors that overexpress HER2. These projects are led by basic and clinical science teams and include the following:

    1. Carolina Breast Cancer Study: Genetic susceptibility for breast cancer subtypes in African Americans and whites
    2. Targeting the Infiltrating Immune Cells in Claudin-low and Basal-type Tumors

    3. Development and Validation of Biomarkers and Targets in Triple Negative Breast Cancers

    4. Defining Kinome Activity for Novel Therapies in Triple Negative Breast Cancer

Researchers involved in SPORE Breast Cancer projects include the following:

Read the latest research news

Carolina Breast Cancer Study enrolls record 3,000 participants - 11/14/2013 

Factors Influencing Delay in Breast Cancer Treatment Differ For African-American and White Women - 7/9/2013 

Anders lab shows advantage to nanotech delivery of therapy for breast cancer brain metastases - 5/3/2013

Perou lab further refines triple-negative breast cancer classification- 2/26/2013

Breast cancer survival featured on UNC's Your Health Radio - 12/28/2012

Carey interviewed by MedPage Today about African Americans and breast cancer  - 11/28/2012

UNC scientist reports ways to improve breast cancer biomarker test- 5/4/2012