UNC Lineberger News

UNC Lineberger faculty headline AACR RAS conference

UNC Lineberger faculty headline AACR RAS conference

The oncogene RAS is linked to 30 percent of human cancers, but the search for a targeted therapy for RAS has remained elusive. Three leading RAS researchers from the University of North Carolina Lineberger Comprehensive Cancer Center are playing leading roles at a conference aimed at discussing recent advances that may lead to new advances in targeting the oncogene.

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Clinical advances should not yet discourage the use of local therapies

Clinical advances should not yet discourage the use of local therapies

Clinical trials that show positive patient response to systemic therapies for cancer should not necessarily lead to reduction in the use of local therapies such as radiation and surgery.

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UNC’s Dr. Jared Weiss joins Lung Cancer Initiative of North Carolina’s Board

UNC’s Dr. Jared Weiss joins Lung Cancer Initiative of North Carolina’s Board

The Lung Cancer Initiative of North Carolina (LCINC), the state’s leading non-profit organization supporting lung cancer research and education, is proud to welcome Dr. Jared Weiss, medical oncologist with UNC Lineberger Comprehensive Cancer Center’s Thoracic Oncology Program, to serve on the board of directors.

UNC’s Dr. Jared Weiss joins Lung Cancer Initiative of North Carolina’s Board - Read More…

Harris comments on major mammography study in The New York Times

Harris comments on major mammography study in The New York Times

UNC Lineberger member Russell Harris, MD, MPH, Professor of Medicine in the UNC School of Medicine and Adjunct Professor of Epidemiology in the UNC Gillings Global School of Public Health, was quoted in two articles in the New York Times about a major study of the efficacy of breast cancer screening published by BMJ (formerly British Medical Journal).

Harris comments on major mammography study in The New York Times - Read More…

Genetic subtypes of bladder cancer reflect breast cancer biology

Genetic subtypes of bladder cancer reflect breast cancer biology

A comprehensive genetic analysis of invasive bladder cancer tumors has found that the disease shares genetic similarities with two forms of breast cancer, according to researchers at the University of North Carolina Lineberger Cancer Center. Bladder cancer, which is the fourth most common malignancy in men and ninth most common in women in the United States, claimed more than 15,000 patients last year.

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Makowski study explores impact of glucose uptake on inflammatory processes

Makowski study explores impact of glucose uptake on inflammatory processes

“This is an important finding because of the field’s increased interest in ‘metabolic reprogramming’ of immune cells. Understanding how macrophage substrate metabolism impacts inflammation is crucial to our being able to develop novel therapies for obesity and diabetes, and even cancer," said study author Liza Makowski, PhD, assistant professor of nutrition at the Gillings School and member of the UNC Lineberger Comprehensive Cancer Center.

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UNC Lineberger receives jointly awarded $1 million research grant to investigate novel target in melanoma

The $1 million award from the Melanoma Research Alliance and the Saban Family Foundation will support research to improve the treatment of melanoma, the most aggressive type of skin cancer.

UNC Lineberger receives jointly awarded $1 million research grant to investigate novel target in melanoma - Read More…

NIH grant to improve efficiency of chemotherapy drugs

NIH grant to improve efficiency of chemotherapy drugs

A team led by Cyrus Vaziri, PhD, and William Janzen at the University of North Carolina at Chapel Hill has received a grant from the National Institutes of Health for research that could help make chemotherapy drugs more effective.

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Early tumor response from stereotactic radiosurgery predicts outcome

Early tumor response from stereotactic radiosurgery predicts outcome

The response of a patient with metastatic brain tumors to treatment with stereotactic radiosurgery in the first six-to-twelve weeks can indicate whether follow-up treatments and monitoring are necessary, according to research conducted at the University of North Carolina.

Early tumor response from stereotactic radiosurgery predicts outcome - Read More…

Application sought for 2014 Marci K. Campbell Dissertation Award

The UNC Lineberger Comprehensive Cancer Center announces The Marci Kramish Campbell Dissertation Award, a competitive $5,000 award to recognize excellence in dissertation research focused on cancer and the population sciences. This cash award goes directly to the recipient and can be used for any purpose.

Application sought for 2014 Marci K. Campbell Dissertation Award - Read More…

Nature Reviews features Smith bladder cancer research

The journal highlights research performed by UNC Lineberger member Angela Smith, MD, that links a loss of muscle mass, known as sarcopenia, in women to complications from a cystectomy. Women who experienced sarcopenia were found to have a 43 percent chance of major complications compared to 10 percent for women who did not experience muscle loss.

Nature Reviews features Smith bladder cancer research - Read More…

Improved ultrasound imaging provides an alternative way of visualizing tumors

Improved ultrasound imaging provides an alternative way of visualizing tumors

While ultrasound provides a less expensive and radiation-free alternative to detecting and monitoring cancer compared to technologies such as X-rays, CT scans and MRIs, the lower clarity and resolution of ultrasound has limited its use in cancer treatment. Researchers at the University of North Carolina at Chapel Hill have overcome this limitation by combining ultrasound with a contrast agent comprised of micro-sized bubbles that pair with an antibody produced at elevated levels by many cancers.

Improved ultrasound imaging provides an alternative way of visualizing tumors - Read More…

A powerful technique to further understanding of RNA

Qi Zhang sees himself as a warrior. In his lab at the University of North Carolina at Chapel Hill, he wages war on genetic diseases such as cancer and heart disease on a battlefield measured with single atoms.

A powerful technique to further understanding of RNA - Read More…

MSN Student Sean Gallagher Receives ONS Fellowship

MSN Student Sean Gallagher Receives ONS Fellowship

The Oncology Nursing Society Foundation selected MSN student Sean Gallagher, RN, for a 2013 APN/DNP Student Fellowship. Mr. Gallagher's fellowship will cover the costs of his research project "Survivors of HPV-Related Oropharyngeal Cancer--Knowledge of Human Papillomavirus (HPV) and Impact of HPV on Sexual Intimacy."

MSN Student Sean Gallagher Receives ONS Fellowship - Read More…

Best Doctors in America® 2014 list includes 53 UNC Lineberger physicians

Best Doctors in America® 2014 list includes 53 UNC Lineberger physicians

The annual compilation of The Best Doctors in America® includes 53 physicians affiliated with the University of North Carolina’s Lineberger Comprehensive Cancer Center.

Best Doctors in America® 2014 list includes 53 UNC Lineberger physicians - Read More…

Endeavors - Radiation Revolution

Sha Chang, Otto Zhou, and collaborators have built the first small device that can produce these kind of microbeams, opening up a new area of research for cancer scientists.

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Carey on breast cancer at MedPage Today

Dr. Lisa Carey, MD, medical director of the UNC Breast Center and associate director for clinical science at UNC Lineberger Comprehensive Cancer Center, is one of the experts interviewed by MedPage Today on recent advances in cancer research.

Carey on breast cancer at MedPage Today - Read More…

Top of the Line - Five questions with Dr. Sharpless

Top of the Line - Five questions with Dr. Sharpless

The next chapter in the story of UNC Lineberger Comprehensive Cancer Center begins with a new director, Ned Sharpless, an oncologist with a story to tell.

Top of the Line - Five questions with Dr. Sharpless - Read More…

Cancer patient out-of-pocket costs play major role in treatment adherence

Cancer patient out-of-pocket costs play major role in treatment adherence

The cost of insurance co-payments for cutting-edge pharmaceuticals can vary widely from patient to patient. When the patient’s share of prescription costs becomes too high, many patients skip doses or stop taking medication entirely, according to research conducted at the University of North Carolina.

Cancer patient out-of-pocket costs play major role in treatment adherence - Read More…

The Charlotte Observer - Mersereau comments on fertility preservation for young adults battling cancer

Dr. Jennifer Mersereau, a fertility preservation specialist at UNC Cancer Care, comments on the promise and challenge of fertility preservation for individuals battling cancer.

The Charlotte Observer - Mersereau comments on fertility preservation for young adults battling cancer - Read More…

UNC Lineberger announces 2013 Excellence Awards

UNC Lineberger Comprehensive Cancer Center and UNC Cancer Care honored four employees with 2013 Excellence Awards.

UNC Lineberger announces 2013 Excellence Awards - Read More…

Associated Press - Coach Hatchell vows to coach again

UNC Women's Basketball Coach Sylvia Hatchell talked to the Associated Press about her fight to get back to her basketball program as quickly as possible.

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UNC Department of Urology participates in Movember Campaign

Movember is a national campaign where teams are inspired to raise money, and grow mustaches, to support men’s health.

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John Isner hosts 4th Annual Ebix Charity Challenge

On December 7, 2013, America’s No. 1 tennis player, John Isner, held his annual charity event, the Ebix Charity Challenge, contributing $75,000 to UNC Lineberger

John Isner hosts 4th Annual Ebix Charity Challenge - Read More…

Screening decisions must balance potential benefits with potential patient harms

Screening to detect medical conditions has become standard practice for many diseases, but insufficient attention has been paid to the potential for harm, according to research by a team led by Russell Harris, MD, MPH, of the UNC School of Medicine, UNC Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center member.

Screening decisions must balance potential benefits with potential patient harms - Read More…

End-of-year deadlines for gifts to receive tax benefits for 2014

We are deeply grateful to the thousands of donors who help make UNC Lineberger’s cancer fight possible by supporting innovative and lifesaving cancer research and care. Here are important year-end gift deadlines and reminders to receive tax benefits for calendar 2014.

End-of-year deadlines for gifts to receive tax benefits for 2014 - Read More…

Evans on 23andMe genetic testing controversy in The Cancer Letter

James Evans, MD, PhD, published his thoughts on the 23andMe genetic testing controversy in the Dec. 13 issue of The Cancer Letter.

Evans on 23andMe genetic testing controversy in The Cancer Letter - Read More…

Muss honored with ACTO Richard L. Schilsky Award

Muss honored with ACTO Richard L. Schilsky Award

The award recognizes Hyman B. Muss, MD, for his years of service to the Richard L. Schilsky Cancer and Leukemia Group B cooperative group.

Muss honored with ACTO Richard L. Schilsky Award - Read More…

Combined therapy reduces recurrence in women with small, HER2+ breast cancers

A new study shows combined therapy is linked to a lower chance of recurrence in women with small, HER2+ breast cancers.

Combined therapy reduces recurrence in women with small, HER2+ breast cancers - Read More…

DeSimone named to National Academy of Inventors

DeSimone named to National Academy of Inventors

The National Academy of Inventors Fellows were nominated by their peers for outstanding contributions to innovation.

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UNC Lineberger leadership offers insight at 2013 San Antonio Breast Cancer Symposium

UNC Lineberger leadership offers insight at 2013 San Antonio Breast Cancer Symposium

UNC Lineberger members Charles Perou, PhD, Lisa Carey, MD, Carey Anders, MD, and Hyman B. Muss, MD will present at symposium.

UNC Lineberger leadership offers insight at 2013 San Antonio Breast Cancer Symposium - Read More…

Songwriters connect over cancer treatment and recovery

N.C. Cancer Hospital patient, Jim MacDonald, worked with songwriter, Emily Lynch, to write a song about his cancer experience, "Every Day is Christmas.”

Songwriters connect over cancer treatment and recovery - Read More…

Five Questions for Yisong Wan: Understanding our immunity

Five Questions for Yisong Wan: Understanding our immunity

Five questions for Yisong Wan, PhD, a new Jefferson-Pilot fellow who is uncovering the roles of T cells in disease cures and causes.

Five Questions for Yisong Wan: Understanding our immunity - Read More…

Approaches to pain assessment in cancer clinical trials

Approaches to pain assessment in cancer clinical trials

Director of the Cancer Outcomes Research Program at the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues at the FDA guide drug developers on how to include meaningful pain endpoints when designing cancer trials.

Approaches to pain assessment in cancer clinical trials - Read More…

Daily Tar Heel - Program provides cancer patients student support

The Carolina Pediatric Attention, Love, and Support program pairs UNC students with young people undergoing treatment for cancer and blood disorders, Josephine Yurcaba of the Daily Tar Heel reports.

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News & Observer - UNC Lineberger support group member featured in book review

News & Observer - UNC Lineberger support group member featured in book review

Bruce Ham, one of the original members of the Single Fathers Due to Cancer support group, has written a memoir, “Laughter, Tears and Braids,” about his journey raising three daughters after the death of his wife from cancer.

News & Observer - UNC Lineberger support group member featured in book review - Read More…

Carolina Breast Cancer Study enrolls record 3,000 participants

The largest-ever population-based study of breast cancer in North Carolina is poised to begin the five year follow-up phase.

Carolina Breast Cancer Study enrolls record 3,000 participants - Read More…

UNC Lineberger part of national #GivingTuesday movement

The Tuesday after Thanksgiving is intended to create a national movement around the holidays dedicated to giving.

UNC Lineberger part of national #GivingTuesday movement - Read More…

Supporting others brings healing to cancer survivors

Supporting others brings healing to cancer survivors

A new study led by Christine Rini, PhD, finds that survivors of hematopoietic stem cell transplant, an aggressive treatment for blood cancers, benefited from a two-part peer support process the authors call expressive helping.

Supporting others brings healing to cancer survivors - Read More…

NPR - FDA tells Google-backed 23andMe to stop selling DNA test

James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, was quoted on National Public Radio's All Things Considered regarding the Food and Drug Administration's warning letter sent to the company 23andMe demanding that its saliva test be taken off the market.

NPR - FDA tells Google-backed 23andMe to stop selling DNA test - Read More…

Be The Match bone marrow registry event Dec 2 and 3 on UNC campus

Be The Match bone marrow registry event Dec 2 and 3 on UNC campus

Give back this holiday season by registering with Be The Match on UNC’s campus on December 2 and 3, 2013.

Be The Match bone marrow registry event Dec 2 and 3 on UNC campus - Read More…

Herald-Sun - Grateful for each day

Stella Waugh, a cancer survivor, is thankful to have family together for Thanksgiving, April Dudash of the Durham Herald-Sun reports.

Herald-Sun - Grateful for each day - Read More…

University Gazette - Humphries helps countless children escape through books

University Gazette - Humphries helps countless children escape through books

For the fifth straight year, UNC Libraries and campus collect books for the Pediatric Hematology-Oncology clinic.

University Gazette - Humphries helps countless children escape through books - Read More…

HPV associated with increased risk of HIV infection in men

HPV associated with increased risk of HIV infection in men

A study of 2,519 Kenyan men conducted by researchers at the University of North Carolina revealed that infection with the human papillomavirus (HPV) was associated with a higher subsequent risk of infection with HIV, a precursor to AIDS.

HPV associated with increased risk of HIV infection in men - Read More…

Family House Diaries: Salie Babilonia - How “The Look” Speaks Volumes

A Dare County, N.C., wife and mother of three keeps her spunky, positive spirit intact during treatment for thyroid cancer, buoying herself, her family and her medical team on the journey.

Family House Diaries: Salie Babilonia - How “The Look” Speaks Volumes - Read More…

Probe measuring immune function can be used to determine nanoparticle dosage for patients

Probe measuring immune function can be used to determine nanoparticle dosage for patients

William Zamboni, PharmD, PhD, has developed a probe to measure the body’s immune function to help physicians deliver accurate, individualized doses for cancer patients prescribed nanoparticle-based drugs

Probe measuring immune function can be used to determine nanoparticle dosage for patients - Read More…

UNC Lineberger holds first community-oriented geriatric oncology symposium

The inaugural geriatric oncology symposium, geared toward a lay audience, provided a lively afternoon of presentations, questions and answers, and concluded with a reception on Friday, November 15, 2013.

UNC Lineberger holds first community-oriented geriatric oncology symposium - Read More…

Channing Der presents lecture at Pancreatic Cancer Action Network

Der highlighted recent research findings that have stimulated new experimental directions for improve therapies for pancreatic cancer.

Channing Der presents lecture at Pancreatic Cancer Action Network - Read More…