Susan G. Komen for the Cure has awarded more than $800,000 to researchers with the UNC Lineberger Comprehensive Cancer Center to fund research into fighting cancer.
UNC Gazette - Oliver Smithies and Nobuyo Maeda were born in island countries half a world apart – he in England, she in Japan – but each in their own way found a path to a life in science.
Bob Goldstein, PhD, professor of biology, talks about his career and the promise of cell biology in a profile in the August issue of The Journal of Cell Biology.
A rapidly-dissolvable microneedle patch developed by a UNC team led by Joseph DeSimone, William R. Kenan, Jr. Distinguished Professor of Chemistry and Chemical Engineering, and director of the UNC Institute for Advanced Materials, Nanoscience, and Technology and member of UNC Lineberger, allows for painless injections of medicine and vaccines.
Researchers at the University of North Carolina and the National Institutes for Health have defined the role of the protein vinculin in enabling cell movement. In a paper published in the Journal of Cell Biology, Sharon Campbell, PhD, professor of Biochemistry and Biophysics and member of UNC Lineberger Comprehensive Cancer Center, and Clare Waterman of the National Heart, Lung and Blood Institute at the National Institutes of Health showed that cell mobility occurs through the interactions between the protein vinculin and the cytoskeletal lattice formed by the protein actin. By physically binding to the actin that makes up the cytoskeleton, vinculin operates as a form of molecular clutch transferring force and controlling cell motion.
When F-actin binds vinculin, actin flow rate is slowed and the cell can move forward. When vinculin is impaired in F-actin binding, F-actin does not engage the focal adhesion and actin retrograde flow increases. This limits directional movement and incre
Like a toddler in need of a nap or a snack, the cells of our bodies can turn a bit sour under conditions of stress or nutrient deprivation. The pH levels inside these cells – starved, perhaps by a heart attack or other injury – have been known to drop dramatically in a cry for help.
A team of researchers has published their analysis of survival rates among study participants in the 2003 Prostate Cancer Prevention Trial showing that the prostate drug finasteride does not decrease survival after a diagnosis of prostate cancer. Their 2003 publication found that while the drug finasteride significantly reduced the risk of prostate cancer, it was associated with an increased risk of high-grade disease and possibly decreased survival.
"Scientists say blueberries powerful antioxidants and anthocyanins make them one of nature's top cancer fighters, two things that hit home for North Carolina women's basketball coach Sylvia Hatchell."
Since 2011, the University of North Carolina has partnered with the government of Malawi to establish a pathology laboratory in the nation’s capital, building on an existing decades-long collaboration. The laboratory has provided an invaluable service to patients and has also built capacity at a national teaching hospital, according to an analysis of the first 20 months of operation published August 7 online by PLOS ONE.
UNC Lineberger scientists Blossom Damania, PhD, Dirk Dittmer, PhD, and Liza Makowski, PhD, have been awarded two-year National Cancer Institute Provocative Questions grants.
Katy Jones has been hired as director of communications and marketing for the UNC Lineberger Comprehensive Cancer Center, effective August 19, 2013.
On August 20, 2013, UNC Lineberger held a reception to honor Charles M. “Chuck” Perou, PhD, for his 2013 Hyman L. Battle Distinguished Cancer Research Award.
An article in the New York Times Magazine profiled work by Barbara L. Fredrickson, Kenan Distinguished Professor of psychology in the College of Arts and Sciences, in partnership with Steven Cole, PhD, Professor of Medicine and Psychiatry and Biobehavioral Sciences in the University of California Los Angeles School of Medicine, into the genomic effects of happiness.
The North Carolina Biotechnology Center awarded more than $460,000 in grants to support research and infrastructure needs of members of the UNC Lineberger Comprehensive Cancer Center researching cancer and cell biology.
David Ollila, MD, professor of surgery, has been appointed to the James H. and Jesse E. Millis Distinguished Professorship. The $1.5 million professorship was established by their son, William (Bill) Millis in honor of his parents, Jim and Jesse Millis of High Point, N.C.
Encouraging physicians to recommend human papillomavirus (HPV) vaccine to adolescent boys and their parents - and educating the boys and their families about the importance of receiving the vaccine - are essential to reducing the cancers this virus can cause.
Noel Brewer, PhD
Ethan Basch, MD, Director, Cancer Outcomes Research Program at UNC Lineberger, discussed incorporating measurements of patient well-being into developing new treatments with CancerNetwork writer Anna Azvolinsky in an Aug. 28, 2013 podcast.
As a clinical nurse IV in the outpatient clinics of N.C. Cancer Hospital, Collier plays many roles from nurse manager to caring for patients. He's used to playing different roles though as he's been into drama and theater about as long as he's been in nursing
As the clinical use of genomic testing expands, the practical and ethical considerations of using the technology to screen newborns for genetic conditions will be the focus of a new study undertaken at the University of North Carolina.
Drs. Cynthia Powell and Jonathan Berg
Racial disparities in the treatment and outcome of breast cancer patients arise from a combination of biological, social and financial causes. Understanding how these complex factors influence interactions between patients and the medical community is key to reducing the gaps in treatment and mortality between racial groups, according to researchers at the University of North Carolina.
Stephanie Wheeler, PhD, MPH
Stephanie Wheeler, PhD, MPH
William Roper, MD, MPH, Dean of the School of Medicine, Vice Chancellor for Medical Affairs, and CEO of University of North Carolina Health Care System, announces the appointment of Norman "Ned" Sharpless, MD, as director of the University of North Carolina Lineberger Comprehensive Cancer Center, effective January 1, 2014.
Dr. Oliver Smithies won the Nobel Prize for his research in gene modification. What you may not know is that since he was a child, he's been enthralled with flying.
Governor Pat McCrory and First Lady Ann McCrory proclaimed September 13 as Childhood Cancer Awareness Day in North Carolina
The Honorable Pat McCrory Governor of the State of North Carolina, and First Lady Ann McCrory visited the North Carolina Children’s Hospital on September 13 to proclaim that day as Childhood Cancer Awareness Day in North Carolina.
E. Claire Dees, MD, associate professor of medicine, and Peter Voorhees, MD, associate professor of medicine, have been appointed to leadership positions in UNC Lineberger Comprehensive Cancer Center. Dr. Dees will serve as medical director of the Clinical Protocol Office and Dr. Voorhees will serve as chair of the Protocol Review Committee.
An 82-year-old resident of Aurora, N.C., is referred to UNC Hospitals for treatment of a nasal cavity cancer in the post of tissue between his nostrils. A multidisciplinary treatment decision, the support of his family and a stay at SECU Family House see him through.
Dr. Cynthia Powell of N.C. Children's Hospital and Dr. Jonathan Berg of UNC Lineberger Comprehensive Cancer Center will answer your questions in a live Facebook chat at noon (12 p.m.) Eastern time on Thursday, Sept. 26.
The national Pink Heals Tour visited UNC on Friday, September 20 with a fleet of pink fire trucks, a bus and emergency vehicles. Chapel Hill Fire Department, the host for the visit, brought their Carolina Blue fire truck.
Prostate cancer treatment delays onset of pain and quality of life deterioration in men with metastatic prostate cancer
Abiraterone acetate, a recently FDA-approved drug used to treat men with metastatic castration-resistant prostate cancer, significantly delays progression of pain and quality of life deterioration when taken in conjunction with prednisone.
Physicians experience increased effort and uncertainty in cross-coverage of radiation oncology patients
Radiation oncology physicians who encounter an unfamiliar case when cross covering for another physician experience higher levels of perceived workload and may perhaps also effects on performance, according to research conducted at the University of North Carolina.
Post-doctoral fellows Scott Rothbart, PhD; Gidi Shemer, PhD; and Angela Wahl, PhD, are the recipients of the Joseph S. Pagano Award for a paper by a postdoctoral fellow published in 2012.
UNC and Wake Forest awarded FDA, NIH grant to create Center for Regulatory Research on Tobacco Communications
Although cigarette use has declined among Americans, regulators face the challenge of communicating the dangers of new tobacco products along with reaching smokers in diverse communities who may not respond to traditional forms of anti-tobacco communication. To address these issues, the U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) announced today that they are awarding a $19.4 million, five-year grant to fund a center at the University of North Carolina that will study issues related to tobacco prevention communication and regulation.
The UNC School of Medicine’s Division of Hematology/Oncology held its first annual retreat on September 6, 2013 at the Rizzo Center in Chapel Hill to discuss the academic mission and future goals of the division.
UNC Lineberger kicked off its Blue Ribbon Gala on September 27, 2013, gathering more than 450 people to celebrate advancements in cancer care at UNC. The black-tie event raised more than $225,000 for UNC Lineberger.
Over 100 physicians, nurses, staff, and patients from UNC and Rex formed the Famous Amos team for the Third Annual Pink Shamrock 5K in Raleigh, NC.
Peer support interventions have traditionally and successfully been used to address health promotion and prevention, such as increasing cancer screening. UNC researchers have published the first study to examine whether enhancing the skills of community-based peer support can help people living with persistent and serious illness.
New test uses PAM50 breast cancer gene signature discovered by UNC’s Perou
Colon Cancer Coalition funds UNC Lineberger to reduce barriers to screenings for vulnerable populations
A local 5K run and walk, Get Your Rear in Gear, raises money to support colon cancer screening programs.
Cowher joins Coach Williams, his assistant coaches, and Woody Durham at this seated breakfast and one-of-a-kind live auction event later this month.
Funds to be used for minimizing the toxicity of chemotherapy
Bone marrow cells treated with Cdk4 inhibition (left) do not express chemotherapy induced multinucleation. Cells treated with chemotherapy only (right) suffer cellular damage and multinucleation.
Patients with poor nutritional status before bladder cancer operation have a higher risk of postoperative complications
New ACS NSQIP® study identifies low blood albumin level as an independent risk factor for surgical-related health problems after radical cystectomy
Shelley Earp is not going anywhere, but at year’s end he will leave a position he has held for the past 16 years as director of the UNC Lineberger Comprehensive Cancer Center.
American No. 1 and North Carolina native John Isner to host charity exhibition featuring Andy Roddick
Fourth Annual Ebix Charity Challenge returns to Isner’s hometown of Greensboro, N.C. on December 7, 2013.
Cure Cancer Starter is a nonprofit site taking the Kickstarter approach to raising funds for much-needed research and clinical trials in the fight against cancer.
Sylvia Hatchell is temporarily stepping away from coaching due to a recent diagnosis of leukemia.
Only half of the men who receive a prostate cancer diagnosis consult with more than one type of physician before deciding on a course of treatment.
The grant will be used to further research to globally understand regulated protein degradation and how this contributes to normal cellular functions that are dysfunctional in cancer.
Football fans gave cancer “the boot” when the Tar Heels faced off with Boston College in Kenan Stadium
The University of North Carolina at Chapel Hill campus is buzzing with anticipation as the beginning of basketball season approaches this Friday, October 25. And the Tar Heels are kicking it off with support for UNC Lineberger.
Join UNC Health Care at 11:00 a.m. Eastern time on Friday, Nov. 1, for a discussion of how fathers cope with the loss of their wife or partner, meet the demands of sole parenthood, and manage their children's grief.
Five questions for Ronald Chen, a James Woods Young Faculty Award recipient dedicated to bettering treatment for cancer patients.
Funds from the campaign will support programs that benefit patients and families receiving cancer treatment at the N.C. Cancer Hospital.
Coach Roy Williams’ 9th annual Fast Break Against Cancer kicks off basketball season with live auction breakfast event.
Charles Perou’s test can help patients decide on a course of treatment.
In the article, "Do you want to know what will kill you?" at Salon.com, Jim Evans MD, PhD, Director of Clinical Cancer Genetics and UNC Lineberger member discusses the pros and cons of consumer-marketed genetic testing.
The UNC Lineberger-sponsored conference featured several UNC-affiliated faculty and graduates.
UNC clinical geneticists Jonathan Berg and James Evans spearhead an ambitious project to catalog all genetic variations implicated in disease.
In the editorial, "Misperceptions on electronic health records" published in the News & Observer, Lawrence Marks, MD, Chair of Department of Radiation Oncology and UNC Lineberger member explains on the benefits and drawbacks of electronic health records.
Help her reach her 2,000-hat goal by December 16.
The Breast Cancer Research Foundation continues its longstanding support of research at UNC Lineberger with $960,000 in awards to four researchers working to discover the causes and find better treatments for breast cancer.
Walking program reduces joint stiffness in older breast cancer survivors on aromatase inhibitor therapy
After six weeks of walking, the mean joint pain scores among the participants decreased by 10 percent, fatigue decreased by 19 percent, and joint stiffness decreased by 32 percent.
The three-year contract is funded by the Patient-Centered Outcomes Research Institute (PCORI).
The five-year grant recognizes the nation’s most innovative young scientists.
GlaxoSmithKline drug-discovery competition winners aim to find a new cancer therapy and a novel way to regulate male fertility, projects spearheaded by scientists at the UNC School of Medicine.
A new microbeam emitter developed at the University of North Carolina at Chapel Hill by a team led by UNC Lineberger member Otto Zhou has the potential to bring a promising new form of radiation therapy into clinical use.
WCHL named Lisa Edwards a Hometown Hero for November 6, 2013. Each weekday the station selects a Hometown Hero who goes “over and above the call of duty,” exemplifying excellent service and dedication to others in the community.
Book drive seeks 10,000th book for the Pediatric Oncology Clinic.
Stereotactic body radiation therapy is an effective treatment option that is cost-effective and convenient for patients.
Matthew Nielsen, MD, MS, FACS, presents on "Active Surveillance for Prostate Cancer" for the Global Grand Rounds hosted by Best Doctors.
Five questions for Greg Wang, a new Jefferson-Pilot fellow searching for better ways to shut down cancer cells.
When celebrities battle cancer, their stories make headlines around the world. Whether announcing their prognosis, seeking treatment or losing their battle, celebrities faced with cancer have a profound impact on the public – one that leads to increased interest in cancer information and screening, according to research by the University of North Carolina.
Women who are obese face an increased risk of developing an aggressive sub-type of breast cancer known as ‘basal-like’, according to research conducted at the University of North Carolina at Chapel Hill.
Der highlighted recent research findings that have stimulated new experimental directions for improve therapies for pancreatic cancer.
The award is the highest distinction awarded by the American Association of Pharmaceutical Scientists.
The inaugural geriatric oncology symposium, geared toward a lay audience, provided a lively afternoon of presentations, questions and answers, and concluded with a reception on Friday, November 15, 2013.
William Zamboni, PharmD, PhD, has developed a probe to measure the body’s immune function to help physicians deliver accurate, individualized doses for cancer patients prescribed nanoparticle-based drugs
A Dare County, N.C., wife and mother of three keeps her spunky, positive spirit intact during treatment for thyroid cancer, buoying herself, her family and her medical team on the journey.
In October 2013, Adam Goldstein, MD, MPH, embarked on an incredible journey taking him to the heartland of civilization's beginning.
A study of 2,519 Kenyan men conducted by researchers at the University of North Carolina revealed that infection with the human papillomavirus (HPV) was associated with a higher subsequent risk of infection with HIV, a precursor to AIDS.
For the fifth straight year, UNC Libraries and campus collect books for the Pediatric Hematology-Oncology clinic.
Stella Waugh, a cancer survivor, is thankful to have family together for Thanksgiving, April Dudash of the Durham Herald-Sun reports.
Give back this holiday season by registering with Be The Match on UNC’s campus on December 2 and 3, 2013.
James P. Evans, MD, PhD, Bryson Distinguished Professor of Genetics and Medicine, was quoted on National Public Radio's All Things Considered regarding the Food and Drug Administration's warning letter sent to the company 23andMe demanding that its saliva test be taken off the market.
A new study led by Christine Rini, PhD, finds that survivors of hematopoietic stem cell transplant, an aggressive treatment for blood cancers, benefited from a two-part peer support process the authors call expressive helping.
The Tuesday after Thanksgiving is intended to create a national movement around the holidays dedicated to giving.
The largest-ever population-based study of breast cancer in North Carolina is poised to begin the five year follow-up phase.
Bruce Ham, one of the original members of the Single Fathers Due to Cancer support group, has written a memoir, “Laughter, Tears and Braids,” about his journey raising three daughters after the death of his wife from cancer.
The Carolina Pediatric Attention, Love, and Support program pairs UNC students with young people undergoing treatment for cancer and blood disorders, Josephine Yurcaba of the Daily Tar Heel reports.
Director of the Cancer Outcomes Research Program at the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues at the FDA guide drug developers on how to include meaningful pain endpoints when designing cancer trials.
Five questions for Yisong Wan, PhD, a new Jefferson-Pilot fellow who is uncovering the roles of T cells in disease cures and causes.
N.C. Cancer Hospital patient, Jim MacDonald, worked with songwriter, Emily Lynch, to write a song about his cancer experience, "Every Day is Christmas.”
UNC Lineberger members Charles Perou, PhD, Lisa Carey, MD, Carey Anders, MD, and Hyman B. Muss, MD will present at symposium.