UNC Lineberger News

UNC scientist reports ways to improve breast cancer biomarker test

UNC scientist reports ways to improve breast cancer biomarker test

American and Spanish researchers report potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests.

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Review study makes recommendations to enhance Cancer Comparative Effectiveness Research

Which treatment for prostate cancer is most effective? Will a specific combination of cancer drugs increase patient survival for colon cancer? As the pace of scientific discovery continues to accelerate, patients and their providers face more choices and decisions about how to address their health care needs, and information that can help inform their decisions is often hard to find.

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Stem cells poised to self-destruct for the good of the embryo

Stem cells poised to self-destruct for the good of the embryo

Embryonic stem cells are primed to kill themselves if damage to their DNA makes them a threat to the developing embryo. UNC researchers reveal how they do it.

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DeSimone elected into National Academy of Sciences

DeSimone elected into National Academy of Sciences

Dr. Joseph DeSimone, PhD, Chancellor's Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill, has been elected into the National Academy of Sciences, one of the highest honors that a U.S. scientist or engineer can receive.

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Milowsky comments on new therapies for bladder cancer

Milowsky comments on new therapies for bladder cancer

Matthew Milowsky, MD, was recently quoted in the online journal Health News Digest on new therapies for bladder cancer.

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Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award

Joseph S. Pagano receives 2012 Battle Distinguished Cancer Research Award

Joseph S. Pagano, MD, has been awarded the fifth annual Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research. Dr. Pagano is the director emeritus of UNC Lineberger Comprehensive Cancer Center.

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UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery

UNC study shows potential to revive abandoned cancer drug by nanoparticle drug delivery

Current nanomedicine research has focused on the delivery of established and novel therapeutics. But a UNC team is taking a different approach.

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36th Annual UNC Lineberger Scientific Symposium

UNC Lineberger’s 36th annual scientific symposium drew large crowds, with over 450 participants.

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Armistead receives Mentored Clinical Scientist Development Award

Armistead receives Mentored Clinical Scientist Development Award

Paul Armistead, MD, PhD, has received a grant of more than $396,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study leukemia stem cell-associated minor histocompatibility antigens.

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UNC junior’s research honored at American Association for Cancer Research meeting

UNC junior’s research honored at American Association for Cancer Research meeting

UNC junior Molly DeCristo attended her first international scientific meeting, but not just as a participant. The American Association for Cancer Research (AACR) honored her poster with a rosette, judging it as “highly rated,” among the top 2.5 percent of those submitted.

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Joyce Wilson: On Trips of a Lifetime, Planned and Unplanned

A Wayne County woman doesn’t let cancer, its treatment or its recurrence get in the way of her plans to attend her oldest granddaughter’s high school graduation or her own 45th high school reunion.

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Intensity Modulated Radiation Therapy optimal for localized prostate cancer

Chapel Hill - A treatment for localized prostate cancer known as Intensity Modulated Radiation Therapy (IMRT) is better than conventional conformal radiation therapy (CRT) for reducing certain side effects and preventing cancer recurrence, according to a study published in the April 18, 2012 issue of the Journal of the American Medical Association. In 2012, approximately 241,740 American men will be diagnosed with prostate cancer.

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International panel recommends new model for breast cancer care

CHAPEL HILL, N.C. - As the number of breast cancer survivors increases, now estimated at 2.8 million, more will be living with the chronic effects of cancer treatments or with advanced disease.

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Coghill receives grant to study graft versus host disease

Coghill receives grant to study graft versus host disease

James Coghill, MD, has received a grant of more than $529,000 from the National Heart, Lung and Blood Institute (part of the National Institutes of Health) to study a promising target for new therapies to combat graft versus host disease, a serious complication of treatment for many blood cancers.

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UNC scientists describe protein that protects against colon cancer

Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.

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Three-dimensional RNA modeling opens scientific doors

Chapel Hill, NC – In a paper published today in the journal Nature Methods, a team from the University of North Carolina at Chapel Hill demonstrates a simple, cost-effective technique for three-dimensional RNA structure prediction that will help scientists understand the structures, and ultimately the functions, of the RNA molecules that dictate almost every aspect of human cell behavior. When cell behavior goes wrong, diseases – including cancer and metabolic disorders – can be the result.

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UNC scientists describe protein that protects against colon cancer

Chapel Hill - A family of proteins is yielding new information about how it contributes to the development of gastrointestinal disease and cancer. A team of UNC scientists reports that in pre-clinical models, the absence of a protein called NLRP12 significantly increases susceptibility to colitis-associated colon cancer.

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Ten minutes could save your life: FREE Head & Neck Cancer Screenings

UNC Health Care will offer free screenings during Oral, Head and Neck Cancer Awareness Week, on Wednesday, April 25, from 1 - 4 p.m. in the Ear, Nose, & Throat Clinic on the ground floor of the N.C. Neurosciences Hospital.

Ten minutes could save your life: FREE Head & Neck Cancer Screenings - Read More…

Kinase test may yield big gains for drug-resistant cancers

Chapel Hill, NC – In a paper published today in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases “en masse”, enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies.

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Gene switches do more than flip “on” or “off”

Gene switches do more than flip “on” or “off”

Chapel Hill - Anyone who’s tried a weekend home improvement project knows that to do a job right, you’ve got to have the right tools. For cells, these “tools” are proteins encoded by genes.

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Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting

Dr. Nancy DeMore and UNC colleagues present triple-negative breast cancer finding at national meeting

Nancy DeMore, MD, and colleagues presented an abstract at the recent Society of Surgical Oncology 65th annual cancer symposium held in Orlando, Florida in March. Dr. DeMore is an associate professor of surgery and a member of UNC Lineberger.

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UNC’s Neuro-oncology program recognizes Ependymoma Awareness Day on April 19th

UNC’s Neuro-oncology program recognizes Ependymoma Awareness Day on April 19th

UNC Cancer Care’s neuro-oncology program will recognize Ependymoma Awareness Day on April 19th, as part of the program’s overall efforts to increase public awareness of this rare tumor and the need for clinical studies to improve early diagnosis, standardize treatment and improve the health status of those living with this disease.

UNC’s Neuro-oncology program recognizes Ependymoma Awareness Day on April 19th - Read More…