UNC Lineberger News

UNC researchers identify important step in sperm reprogramming

UNC researchers identify important step in sperm reprogramming

CHAPEL HILL – When sperm meets egg, the chemical instructions that tag sperm cells must be erased so that human life can start anew. One way these instructions are erased is through demethylation, the removal of specific chemical tags or methyl groups that dot the underlying DNA of cells. Though scientists have known about this phenomenon for a decade, exactly how such “reprogramming” occurs has proved elusive.

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