The UNC Brain Metastasis Specialty Clinic seeks to offer a portfolio of clinical trials. Some of our most exciting trials are featured below.

I3Y-MC-JPBO: A Phase 2 Study of Abemaciclib in Patients with Brain Metastases Secondary to Hormone Receptor Positive Breast Cancer, Non-small Cell Lung Cancer, or Melanoma

PI: Carey Anders, MD

Study Coordinator:

Contact: 919-974-8657

MM-398-01-01-02: A Phase 1 Study in Patients Treated with MM-398 (Nanoliposomal Irinotecan, nal-IRI,) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment

PI: Carey Anders, MD

Study Coordinator:

Contact: 919-974-8657

TBCRC-022: A Phase II Trial of HKI-272 (Neratinib) and Capecitabine for Patients with Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer and Brain Metastases

PI: Carey Anders, MD

Study Coordinator:

Contact: 919-974-8657

MM-302-02-02-03: A Randomized, Multicenter, Open Label Study of MM-302 plus Trastuzumab vs. Chemotherapy of Physician’s Choice plus Trastuzumab in Anthracycline Naive Patients with Locally Advanced/Metastatic HER2-Positive Breast Cancer

PI: Carey Anders, MD

Study Coordinator:

Contact: 919-974-8657

Search all UNC Lineberger Clinical Trials