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February 18, 2019

Researchers identify cluster of N.C. counties with higher colorectal cancer death rates

University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered county-level factors linked to higher colorectal cancer mortality rates in a cluster of counties in northeastern North Carolina. In the journal Cancer Epidemiology, researchers report 10 counties in northeastern North Carolina are part of a cluster of counties with higher rates of colorectal cancer …

Megan Agajanian, Alison Axtman, M. Ben Major, PhD

January 31, 2019

Scientists uncover mechanism cells use to deactivate a signal that’s hyperactive in cancer

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have discovered how a cellular signal that’s abnormally hyperactive in cancer can be deactivated. In the journal Cell Reports, UNC Lineberger’s M. Ben Major, PhD, and colleagues published a paper on how the WNT signaling pathway is regulated. WNT proteins increase tumor onset, growth …