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Endometrial Cancer Fast Facts

  • Endometrial cancers account for >90% of all uterine cancers, the most common gynecologic cancer in the U.S.
  • Over the last 10 years, rates of new cases and deaths have been rising on average each year
  • Endometrial cancer affects mainly post-menopausal women
  • Most cases are diagnosed at an early stage, leading to higher survival (5-year survival for localized disease is at 95%)
  • Black women have a 93% higher 5-year mortality rate from endometrial cancer than White women
  • To date, no other epidemiologic study has used a population-based platform and multifaceted approach to investigate endometrial cancer disparities


CECS Fast Facts

The Carolina Endometrial Cancer Study will be the first comprehensive population-based resource to assess endometrial cancer disparities. This study will also provide important data for integrating tumor biology, access to care, and other factors to identify contributors and potential areas for intervention or development.

Study Design

  • Rapid identification of about 1,800 women with newly diagnosed endometrial cancer living in North Carolina through the North Carolina Central Cancer Registry.
  • Obtain medical records and tumor samples from diagnosis/treatment of endometrial cancer.
  • Collect information on demographics and key factors related to endometrial cancer risk and prognosis via a baseline survey.
  • Re-contact about yearly for 5 years to obtain information on treatments, long-term side effects, quality-of-life, cancer recurrence/metastases etc.

Recruitment Eligibility

  • Female adults aged 20 to 80 at time of diagnosis
  • All racial and ethnic groups
  • Speak English
  • Residents of any of the 100 counties of North Carolina at time of diagnosis
  • Newly diagnosed with endometrial cancer since January 1, 2020



Baseline Survey (Annotated) – Coming soon!

Follow Up #1 Survey (Annotated) – Coming soon!

Follow Up #2 Survey (Annotated) – Coming soon!


Advocacy Partners

ECANA is a multi-stakeholder group of patients, researchers, clinicians and community leaders. For this project, ECANA ambassadors (patient advocates) provide patient insight on study design, recruitment approach, participant retention, and data analysis.


Funding Sources

The study is conducted by the Lineberger Comprehensive Cancer Center and is also affiliated with the Gillings School of Global Public Health at the University of North Carolina at Chapel Hill. It is funded by the University Cancer Research Fund of North Carolina and the University of North Carolina Lineberger Comprehensive Cancer Center.