Program News - UNC Lineberger

Headshots of Kaitlin Morrison and Carrie Lee, and an outline of the state of North Carolina.

UNC Lineberger expands access to cancer clinical trials across North Carolina

UNC Lineberger’s J. Kaitlin Morrison, PhD, and Carrie Lee, MD, PhD, launched a study to investigate whether UNC Health can successfully conduct hybrid cancer clinical trials across the state.

Carey named a ‘Giant’ of breast cancer care

Lisa Carey, MD, ScM, FASCO, was honored by OncLive as one of its 2025 Giants of Cancer Care for her significant contributions advancing the treatment and study of breast cancer.

Cluster of circulating tumor cells and white blood cells.

UNC Lineberger awarded up to $28M to develop an adaptive clinical trial for metastatic breast cancer

UNC Lineberger will lead the development of a next-generation clinical trial for metastatic breast cancer. The new trial design will adapt treatment plans in near real-time by analyzing changes in each patient’s cancer and matching it to the most promising therapy.

Human cells with acute myelocytic leukemia (AML) in the pericardial fluid, shown with an esterase stain at 400x magnification.

Novel drug combination is safe and benefits people with acute myeloid leukemia who have a specific genetic profile

Joshua Zeidner, MD, and colleagues report that a combination therapy that adds a recently approved drug to the current standard of care for newly diagnosed acute myeloid leukemia showed high rates of complete remission in an early-phase clinical trial.

Compilation of photos featuring UNC Lineberger researchers at poster sessions and presentations during the 2025 ASCO Annual Meeting.

UNC Lineberger faculty and trainees present research, receive honors at cancer research meeting

UNC Lineberger faculty and trainees presented research findings and participated in panel discussions at the American Society of Clinical Oncology’s annual meeting in Chicago.

UNC faculty and trainees to present at the world’s largest clinical cancer research meeting

UNC faculty and trainees will share their latest research findings and clinical insights during talks, poster presentations and panel discussions during the American Society of Clinical Oncology’s annual meeting in Chicago, taking place May 30 – June 3.

What are my treatment options for prostate cancer?

Urologic oncologist Matthew Milowsky, MD, FASCO, discusses treatment options if you’ve been diagnosed with prostate cancer.

AACR (American Association for Cancer Research) Annual Meeting 2025 Chicago.

UNC Lineberger and UNC faculty and trainees present findings at AACR annual meeting

Nearly 30 UNC Lineberger and UNC faculty and trainees will present findings and participate during the American Association for Cancer Research annual meeting in Chicago, April 25-30.

Adaptive whole-genome sequencing could transform childhood leukemia diagnosis

UNC Lineberger researchers have demonstrated a faster, more cost-effective approach to analyzing the genetic makeup of pediatric acute leukemia. Determining a cancer’s genomic classification is critical to developing a more effective treatment plan tailored to a patient’s tumor.

Gastrointestinal oncologist discusses increase in younger patients with colorectal cancer

The rise of colorectal cancer cases in people under 45 has steadily increased, prompting concern among oncologists and researchers. Ashwin Somasundaram, MD, talks about colorectal cancer and this concerning trend.

A multiple myeloma physician talking with a nurse in the clinic.

Improved multiple myeloma therapies help patients live longer, better lives

March is Multiple Myeloma Awareness Month, an opportunity to shed light on a disease that accounts for approximately 10% of all blood cancers. Treatment options for multiple myeloma have expanded in recent years, leading to better patient outcomes and longer survival rates.

Human colon cancer cells with the cell nuclei stained red and the protein E-cadherin stained green. E-cadherin is a cell adhesion molecule and its loss signals a process known as the epithelial-mesenchymal transition in which cells acquire the ability to migrate and become invasive.

Immunotherapy and targeted therapy combination proves effective against metastatic colorectal cancer

UNC Lineberger researchers have demonstrated that combining two immunotherapy drugs with a targeted therapy drug proved effective in treating the most common form of metastatic colorectal cancer.

Study now recruiting patients to treat PANcreatic adenocarcinoma with Gemcitabine, Erlotinib, and nAb-paclitaxel (PANGEA)

UNC Lineberger has opened a two-arm clinical trial to determine the optimal combination treatment for patients with advanced unresectable or metastatic basal-like subtype pancreatic ductal adenocarcinoma.

World map with connecting line between North Carolina and Malawi.

Malawi cancer program develops diagnostic breakthrough

Part of UNC Project Malawi, the cancer program provides clinical care, pathology training and other services to the African nation. The program is entering the second phase of developing a low-cost cancer diagnosis method.

Group photo of approximately 60 people who attended the 2025 GI SPORE Investigators Meeting in Chapel Hill.

UNC Lineberger hosts NCI in gastrointestinal cancer SPORE Investigators Meeting

The nation’s top gastrointestinal cancer clinical translational researchers convened in Chapel Hill for the 2025 GI SPORE Investigators Meeting.