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Find a Clinical Trial

View featured trials open for accrual or search our full clinical trial database. Please contact our office if you have any questions or would like to refer a patient.

Open Clinical Trials by Indication

 

Highlighted Studies

Loxo-Ras-20001

The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific genetic mutation (KRAS G12C). Patients must have already received or were not able to tolerate the standard of care, except for specific groups who have not had cancer treatment. The study will last up to approximately 4 years.

Learn More About Loxo-Ras-2001

HARMONY

The HARMONY study hopes to improve care in patients with Metastatic Breast Cancer. The study will obtain information about molecular sub-type and then determine the impact of that information on treatment decisions. Blood samples will be collected at time of enrollment and every 6 months afterwards. In addition, existing samples of tumor tissue will be used for analyses. No extra biopsy is needed! Adult patients on (or before) their first treatment for metastatic breast cancer who are being seen at UNCH or UNC-Rex may be eligible. While sample collections are indefinite, patient’s active participation is expected to last about 30 minutes. The study is ongoing.

Learn More About HARMONY

Common Provider Questions Answered

Reach out via our contact page to be put in touch with our team.

Contact us About Clinical Trials

For a full listing of our open clinical trials, click the below link to our Research For Me website. If you want a disease-specific listing of treatment trials, click the link below to the provider-directed clinical trial matrices.

Search Clinical Trials Open Clinical Trials by Indication

For a specific question about a particular clinical trial, please reach out to our team who will put you in touch with the appropriate study coordinator.

Contact us About Clinical Trials

The length of time it takes to start a patient on a clinical trial depends on the study and disease type, and whether the clinical trial has a waitlist. Most solid tumor treatment trials have a screening window of 2-4 weeks to allow for assessments and eligibility determination.  Hematological malignancy treatment trials vary based on the disease type. The time from consent to start of treatment on leukemia trials averages about a week (though sometimes quicker depending on the details of the study and disease). Lymphoma and multiple myeloma studies average about 2 weeks from consent to start of treatment.

Different studies have different requirements. It is most likely that the patient’s care will need to transferred to UNC for the experimental component at a minimum. UNC Lineberger has a couple of hybrid decentralized clinical trials where many procedures may be performed locally. Please reach out to our team to learn more about current offerings.

Contact us About Clinical Trials

Hybrid decentralized clinical trials (DCTs) are trials in which some or all procedures may be performed by a local health care provider (HCP). UNC Lineberger has several pilot hybrid DCT studies where local HCPs may perform procedures that they are qualified to perform in clinical practice (e.g., physical exams, obtaining vitals) as long as those procedures to not require study-specific training. These trials are designed to ease patient/caregiver burden, increase convenience, and enhance diverse enrollment on clinical trials.

Patient Financial Services

If a patient does not have insurance, or is worried about paying for their medical bills, UNC Health has a dedicated team of Financial Navigators are ready to assist them. As a member of their care team, Financial Navigators are committed to helping them understand the cost of their care. Financial Navigators work closely with their doctors, nurses, and support team to provide them with information needed to make decisions about your care.

Services

  • Explain their insurance benefits
  • Provide cost estimates
  • Explore flexible payment plans
  • Review available assistance programs including: North Carolina Medicaid, UNC Financial Assistance, COBRA Premium Assistance, Pharmacy Assistance
  • Answer questions about their bill

Here to help

If your patient has an unexpected life change, Financial Navigators are there to support them. Please encourage your patient to speak to a Financial Navigator if they have a:

  • Change in employment
  • Loss or change of insurance
  • Concerns paying for their medical care
  • Financial hardship

Connect with a Financial Navigator

Oncology Financial Navigators are available Monday through Friday from 8:30 a.m. until 4:30 p.m. To learn more about the UNC Oncology Financial Assistance program, please call (984) 974-5668 or by emailing UncOncologyFinNav@unchealth.unc.edu.


Comprehensive Cancer Support Program

Dedicated to helping patients and their loved ones with cancer treatment, recovery, and survivorship, the UNC Lineberger Comprehensive Cancer Support Program (CCSP) offers programs and services both during and after your treatment.

Learn about the CCSP


Clinical Trials Patient Navigator

Your patient can also connect with our Clinical Trials Patient Navigator to learn more about clinical trials and participating in research. A Clinical Trials Patient Navigator helps connect patients with resources, which could help make their participation in a trial more possible.

Patient Navigators help guide patients through the health care system, and are a helpful resource.

Learn more about Resource for Patients & the CREATE Program

You, as an outside provider, may contact the UNC provider as desired. There is currently no mechanism for providing real-time updates on clinical trial participants to outside providers.
You may request updates from the treating physician for the patient at UNC.
There may be a waitlist depending on the clinical trial. Please contact the study team for additional details.

Contact us About Clinical Trials

You can help expedite getting your patient on a trial by responding to any contact, particularly medical record request, as soon as possible, to speed up our evaluation process of your patient’s eligibility to participate on a particular study.

Each clinical trial has its own benefits and risks. Your patient may benefit from joining a clinical trial in one of the following ways:

  • If the new treatment works, they may be one of the first people to benefit
  • They may be able to help future cancer patients

Some possible risks include:

  • Expected side effects
  • Unexpected side effects
  • New treatments do not always turn out to be better than, or as good as, standard treatment
  • As with standard treatment, the new treatment may not work for your patient even if it works for other patients

Have questions? Get in touch with our team

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