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Benjamin F. Calvo

Ben Calvo, MD, is a UNC Lineberger Comprehensive Cancer Center Member, Associate Professor of Surgery at UNC-Chapel Hill, Director of the Gastrointestinal Multidisciplinary Oncology Program and Co-Director of the UNC Lineberger GI Oncology Program Clinical Research. Calvo’s specialties include: advanced and recurrent rectal carcinoma, colorectal metastases to liver and breast cancer related procedures.

James F. Newsome Distinguished Professorship
UNC-Chapel Hill
Clinical Research
Gastrointestinal Oncology Program

Area of Interest

Calvo’s research focuses on non-receptor protein-tyrosine kinases (PTKs), which are important in signal transduction from cytoskeletal structures. He is also interested in the EGFR family of receptor tyrosine kinases as they relate to solid malignancies. He is actively pursuing the use of quantitative PCR and biochip technology to determine mRNA levels of these various kinases in carcinomas of the colon, breast and melanomas. Calvo has been actively involved in the development of new techniques for cyroablation of liver metastases from colon cancer as well as participating in a number of active multi-modality therapeutic programs for patients with colon and rectal carcinoma.

Calvo is taking the lead, in conjunction with Dr. Mark Graham from Medical Oncology and Dr. Robert Briggaman from Dermatology, in developing a melanoma program at UNC. Their work will focus on the development of combined chemotherapy and biologic treatments along with novel immunologic strategies that will include vaccine and antibody based efforts.

Find publications on PubMed

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