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Bob Goldstein, PhD, is a UNC Lineberger Comprehensive Cancer Center member and James L. Peacock III Distinguished Professor at the UNC School of Medicine. The Goldstein Lab is researching to discover fundamental mechanisms in cell and developmental biology.

James L. Peacock III Distinguished Professor
UNC-Chapel Hill
Cancer Cell Biology

Area of Interest

We are interested in understanding how cells function during development. We use primarily the model roundworm C. elegans because it allows us to readily combine a large number of useful techniques to address basic questions in cell and developmental biology — techniques of cell biology, experimental embryology, forward and reverse genetics, biochemistry, molecular biology, biophysics, and live imaging of cells and their cytoskeletal components.

Current work in the lab addresses several issues relevant to cancer cell biology — how critical cell shape changes and cell movements are driven, how intercellular signals that are important in cancers can normally polarize cells, and how cell divisions are oriented in specific planes.

We expect that furthering our understanding of such fundamental events in normal cells will contribute to understanding how such events occur aberrantly in disease states.

Find publications on PubMed

Awards and Honors

  • Chapman Family Teaching Award, 2018
  • Guggenheim Fellow, 2007
  • Visiting Fellow of Clare Hall, Cambridge University, 2007;, Elected as Life Member, 2008
  • Phillip and Ruth Hettleman Prize for Artistic and Scholarly Achievement by Young Faculty at UNC-Chapel Hill, 2005
  • Pew Scholar, 2000-2004
  • March of Dimes Basil O’Connor Scholar, 2000-2002
  • Phone Number

    (919) 843-8575 (Office Phone)

  • Address

    616 Fordham Hall

    Biology Dept.

    CB #3280

    Chapel Hill, NC 27599