Associate Professor, Division of Oncology
Director, UNC RNA Discovery Center
Meet Chad Pecot
Area of Interest
I am an Associate Professor at the UNC Lineberger Comprehensive Cancer Center and I specialize in solid tumor malignancies. As a prior cancer patient, my passion is to uncover important findings in cancer biology and translate these to the clinic as rapidly as possible. Since August 2013 I have been an independent investigator at UNC-Chapel Hill. My research career thus far has quickly led to several high-impact discoveries as a result of innovative ideas and establishment of synergistic collaborative teams. I also have a passion for training the next generation of scientists at the doctoral and postdoctoral level. My research is characterized by a harmonization of therapeutic RNA interference, sophisticated modeling of cancer metastasis and the tumor microenvironment, and the integrative use of complex bioinformatic and systems biology approaches to uncover key nodes in cancer networks. Because metastatic spread accounts for the greatest proportion of cancer-related deaths in the U.S. and worldwide, most of my current work uses lung and triple-negative breast cancers as disease models with the hopes that our discoveries will also fundamentally impact treatment paradigms in other aggressive malignancies.
Awards and Honors
- University of North Carolina UCRF Innovator Award, 2019
- Susan G. Komen Career Catalyst Award, 2017
- Free to Breathe Metastasis Research Award, 2016
- Stuart Scott V Foundation/Lung Cancer Initiative Award for Clinical Research, 2016
- William Rippe Award for Distinguished Research in Lung Cancer, 2016
- Lung Cancer Research Foundation Award, 2016
- ASCO Conquer Cancer Foundation Scientific Career Development Retreat, 2016
- Division of Cancer Medicine Achievement in Basic Science Research, 2012
- Invited Lecture: Institutional Grand Grounds (MDACC), 2012
- The Ben F. Love Fellowship in Innovative Cancer Therapies, 2012
- National Institute of Health, Research Loan Repayment Awardee, 2011
- Invited Lecture: Department of Cancer Medicine Grand Rounds (MDACC), 2011
- ASCO Conquer Cancer Foundation Young Investigator Award, 2011
- The Jeffrey Lee Cousins Fellowship in Lung Cancer Research, 2010
- Ruth L. Kirschstein National Research Service Award, 2010
- ASCO Cancer Foundation Merit Award, 2010
- Inducted into Alpha Omega Alpha Honor Society, 2006
- Thomas Brown McClelland Rotary Scholarship, 2005
- Creativity Award (American Cancer Society), 2005
- Thomas Brown McClelland Rotary Scholarship, 2004
- Peter J. Tarjan Award for Excellence in Biomedical Engineering, 2002
News and Stories
UNC Lineberger creates RNA Discovery Center
The UNC RNA Discovery Center, led by Chad Pecot, MD, will cultivate an inclusive community of scientists dedicated to investigating all aspects of RNA biology.
Leading researchers provide insights on aggressive cancers at scientific symposium
UNC Lineberger’s 45th annual Scientific Symposium featured talks on the latest research on pancreatic cancer, tumor microenvironments, metastatic disease and immunotherapy.
A patient’s decision adds immeasurably to knowledge about how to treat lung cancer
Chad Pecot, MD, and colleagues used biospecimens from a patient just after he succumbed to lung cancer to unravel how a KRAS mutation developed resistance to a treatment that had initially proved effective.
A cancer survivor fights back
UNC Lineberger's Chad Pecot, MD — a cancer survivor himself — launched EnFuego Therapeutics with the help of UNC KickStart Venture Services to develop RNA-interference drugs that silence cancer-related gene mutations.