Professor, Division of Oncology
Co-Leader, UNC Lineberger Molecular Therapeutics Research Program
Director, UNC RNA Discovery Center
Meet Chad Pecot
Area of Interest
I am a professor at the UNC School of Medicine and am a Lineberger Comprehensive Cancer Center member, and I specialize in solid tumor malignancies. As a prior cancer patient, my passion is to uncover important findings in cancer biology and translate these to the clinic as rapidly as possible. Since August 2013 I have been an independent investigator at UNC-Chapel Hill. My research career thus far has quickly led to several high-impact discoveries as a result of innovative ideas and establishment of synergistic collaborative teams. I also have a passion for training the next generation of scientists at the doctoral and postdoctoral level. My research is characterized by a harmonization of therapeutic RNA interference, sophisticated modeling of cancer metastasis and the tumor microenvironment, and the integrative use of complex bioinformatic and systems biology approaches to uncover key nodes in cancer networks. Because metastatic spread accounts for the greatest proportion of cancer-related deaths in the U.S. and worldwide, most of my current work uses lung and triple-negative breast cancers as disease models with the hopes that our discoveries will also fundamentally impact treatment paradigms in other aggressive malignancies.
Awards and Honors
- Lung Cancer Initiative Alumni Supplemental Grant, 2023
- University of North Carolina UCRF Innovator Award, 2019
- Susan G. Komen Career Catalyst Award, 2017
- Free to Breathe Metastasis Research Award, 2016
- Stuart Scott V Foundation/Lung Cancer Initiative Award for Clinical Research, 2016
- William Rippe Award for Distinguished Research in Lung Cancer, 2016
- Lung Cancer Research Foundation Award, 2016
- ASCO Conquer Cancer Foundation Scientific Career Development Retreat, 2016
- Division of Cancer Medicine Achievement in Basic Science Research, 2012
- Invited Lecture: Institutional Grand Grounds (MDACC), 2012
- The Ben F. Love Fellowship in Innovative Cancer Therapies, 2012
- National Institute of Health, Research Loan Repayment Awardee, 2011
- Invited Lecture: Department of Cancer Medicine Grand Rounds (MDACC), 2011
- ASCO Conquer Cancer Foundation Young Investigator Award, 2011
- The Jeffrey Lee Cousins Fellowship in Lung Cancer Research, 2010
- Ruth L. Kirschstein National Research Service Award, 2010
- ASCO Cancer Foundation Merit Award, 2010
- Inducted into Alpha Omega Alpha Honor Society, 2006
- Thomas Brown McClelland Rotary Scholarship, 2005
- Creativity Award (American Cancer Society), 2005
- Thomas Brown McClelland Rotary Scholarship, 2004
- Peter J. Tarjan Award for Excellence in Biomedical Engineering, 2002
News and Stories
UNC RNA Discovery Center awards inaugural fellowship grants
The UNC RNA Discovery Center has awarded three fellowship grants to support innovative research investigating various roles of RNA in health and disease.
NCI awards Pecot $1.8 million lung cancer research grant
The grant will support Chad Pecot, MD, and his research investigating the roles circular RNA may have in regulating whether a form of lung cancer will spread beyond the original cancer site.
RNA discoveries drive oncologist’s next chapter
Physician-scientist and cancer survivor Chad Pecot, MD, is focused on RNA discoveries in the lab and the clinic.
Lung Cancer Initiative awards Pecot $100,000 grant
The grant supports Chad Pecot, MD, and his research into the mechanistic and therapeutic implications of co-targeting two genes linked to lung cancer.