Dirk P Dittmer

Dirk P. Dittmer, PhD, is a UNC Lineberger Comprehensive Cancer Center member and Professor in the Department of Microbiology and Immunology at UNC-Chapel Hill. Dittmer Lab’s research goal is to understand viral tumorigenesis, specifically, cancers that are caused by Kaposi sarcoma-associated herpesvirus (KSHV/HHV-8).

UNC-Chapel Hill

Area of interest

25% of human cancers worldwide are infection associated. Our efforts seek to combine translational studies on Kaposi sarcoma and viral lymphoma with genetically engineered mouse models and the detailed molecular investigation of key viral oncogenes. These include microRNAs. We employ high-throughput real-time qPCR and NextGen sequencing as the signature technology platform and are able to rapidly cross-validate the results of experimental approaches into clinical trials.

Secondly, we are actively engaged in the search for new cancer-associated viruses, for instance in cancers which are frequent in low and medium income countries as part of global oncology efforts.

Awards and Honors

  • Fellow American Society for Microbiology (ASM)
  • Member UNC Center for AIDS research (CfAR)
  • Chair of network laboratories for the AIDS malignancies clinical trials consortium (AMC)

Clinical Trials:
NCT01352117 – Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi’s Sarcoma ;

NCT01435018 – Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS

Find publications on PubMed

NC Reach profile