MD, MPH
Professor, Department of Medicine
UNC-Chapel Hill
Cancer Prevention and Control
Gastrointestinal Oncology Programs
Area of Interest
I am a gastrointestinal medical oncologist and clinical researcher. My primary academic focus is on improving the quality of cancer care delivery. I approach this goal through health services research and through leading value and quality initiatives at the UNC Health System.
I am also a clinical trialist and have served as the principal investigator on a number of industry, cooperative and investigator initiated clinical trials. I am an active member the Alliance for Clinical Trials in Oncology, serving on multiple Alliance committees (GI Committee and the Alliance-ACS Cancer Care Delivery Research Committee), the GI Colon Cancer Trials Working Group, and as the Alliance Representative to the Colon Task Force of the NCI GI Steering Committee. In addition to mentoring multiple trainees and junior faculty, I am the Program Director of our Paul Calabresi K12 institutional career development award.
Awards and Honors
- UNC Health Care and Faculty Physicians Carolina Care Excellence Leader, 2016-2019
- Recognition, UpToDate Best Authors in Oncology, 2017
- Best Doctors in America, 2013-2018
- America’s Top Doctor, Castle Connolly/ US News & World Report, 2010
News and Stories

Immunotherapy and targeted therapy combination proves effective against metastatic colorectal cancer
UNC Lineberger researchers have demonstrated that combining two immunotherapy drugs with a targeted therapy drug proved effective in treating the most common form of metastatic colorectal cancer.

Sanoff offers perspective on a promising rectal cancer study in the New England Journal of Medicine
Hanna K. Sanoff, MD, MPH, is the author of a viewpoint that provides a perspective on the evolving treatment of rectal cancer in light of findings from a phase II clinical trial using the drug dostarlimab.