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James M. Coghill

James Coghill, MD, is an associate professor at UNC-Chapel Hill in the Division of Hematology and Oncology.

MD
Associate Professor
UNC-Chapel Hill
Leukemia, Lymphoma, and Myeloma Program

Area of Interest

I am a bone marrow transplant physician with a research interest in acute graft-versus-host disease (aGVHD), an autoimmune like complication that can develop after BMT. Our lab focuses on chemokine receptor biology and lymphocyte trafficking after transplant, with the overriding goal of developing never, more targeted aGVHD therapies. We are particularly interested in CC-Chemokine Receptor 7 (CCR7), a receptor critical for aGVHD pathogenesis. Our research group was the first to publish the structure of a validated CCR7 small molecule antagonist (cosalane), and the first to demonstrate its efficacy as a novel means to prevent aGVHD relevant murine BMT models.

Awards and Honors

  • Phi Kappa Phi Medical Honor Society, 2000
  • 1st place in the Medical Student Research Symposium, 2000
  • Alpha Omega Alpha Medical Honor society (one of 8 students elected during their third year), 1999
  • Sydney Barnam Scholarship for excellence on USMLE part I (99th percentile), 1999
  • Negus Biochemistry Prize, 1997
  • Pathology Prize, 1997
  • Pathology Honor Society, 1997
  • State Discretionary Scholarship, 1996-1997
  • Phi Beta Kappa Honor Society, 1996

Find publications on PubMed

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