Area of Interest
My clinical interest is the treatment of hematological malignancies using immunotherapy and hematopoietic stem cell transplantation (HCT). The complexities of the patients and the long-term impact of transplant on their lives provides ongoing opportunities for research; however, I have special interest in treatment and prevention of HCT complications including infections and graft versus host disease (GVHD) as these areas contribute to both significant morbidity and mortality associated with transplantation.
I serve as the PI locally on several clinical trials for our transplant and cellular therapy patients. Additionally, I am a co-investigator on a national trial through the NHLBI/NCI Blood and Marrow Transplant Clinical Trials Network (BMT CTN). This trial will not only develop a bio-specimen repository for longitudinal systems-based immunologic analysis of the T-Cell Receptor repertoire, microbiome, and T-cell transcriptome with detailed clinical outcomes data, it will also obtain detailed infection complication data including diagnostic criteria, antimicrobial prophylaxis, and treatment for the 300 enrolled patients. Finally, I am also the Scientific Director for the Infection and Immune Reconstitution Working Committee for the Center for International Blood and Marrow Transplant Research (CIBMTR), a large transplant data repository collecting outcomes data from more than 400 transplant centers worldwide.
Awards and Honors
- 2007 Department of Medicine Clinical Excellence Award, University of Minnesota
- 2006 ASBMT/CIBMTR Travel Grant Award
- 2002 ASCO Young Investigator Award
- 2000 Serle/Pharmacia Fellow in Hematology/Oncology
- 1997 Graduate with High Distinction, University of Kentucky College of Medicine