Melina R. Kibbe

Melina Kibbe is a UNC Lineberger Comprehensive Cancer Center member, Professor, and Chair of Surgery. Kibbe research is focused on helping patients with vascular diseases.

MD
Colin G. Thomas, Jr. Distinguished Professor, Chair of Surgery
UNC- Chapel Hill
Molecular Therapeutics

Area of interest

My clinical practice is focused on the care of patients with vascular disease, including, but not limited to, peripheral arterial disease, carotid artery disease, abdominal aortic aneurysmal disease, and hemodialysis access. A long-term goal for my research efforts as a vascular surgeon-scientist is to develop novel drug-releasing therapies for patients with vascular disease. Toward that goal, I have collaborated with chemists, biomedical engineers, material scientists, and engineers, among others. Together, we have developed nitric oxide-based therapeutics, including nitric oxide-releasing vascular grafts, perivascular wraps, and novel biodegradable elastomeric arterial stents. Over the past decade, our lab has developed a suite of targeted, drug-delivering nanotherapeutics for the vasculature. These therapies have been designed to prevent neointimal hyperplasia, prevent hemorrhage, and target atherosclerosis to induce plaque reduction. As part of developing novel drug-releasing technologies for the vasculature, our lab has been committed to understanding how these therapies impact the vascular wall. By having a greater understanding of their impact, better therapies can be designed and developed. In addition, we have had a great interest in understanding the role of sex as well as the metabolic state in regulating the arterial injury response. Evaluating sex as a variable in biomedical and clinical research is incredibly important to the advancement of medicine. As such, I have studied how investigators have conducted sex biased versus sex inclusive research in the medical literature. Some of these efforts have led to policy change with the National Institutes of Health, and initiatives with the FDA and the federal government.

Awards and Honors

  • 2019 University of Chicago Distinguished Service Award
  • 2019 European Surgical Association, Honorary Fellow
  • 2019 Presidential Citation, Association of VA Surgeons
  • 2019 American Medical Student Association Women Leaders in Medicine Award
  • 2018 Halsted Society (elected)
  • 2017 Southern Surgical Association
  • 2017 American Institute for Medical and Biological Engineering
  • 2017 Thomas Sheen Award, New Jersey Chapter, American College of Surgeons
  • 2016 National Academy of Medicine
  • 2016 American Society for Clinical Investigation
  • National Academy of Medicine, 2016
  • Tripartite Award, Landsberg Research Day, Feinberg School of Medicine, Northwestern University, 2016
  • George Joost Outstanding Teacher in Structure-Function, NU Feinberg School of Medicine, 2011
  • Presidential Early Career Award for Scientists and Engineers, 2009
  • Outstanding Teacher Award, NU Feinberg School of Medicine, 2008, 2009, 2010, 2011, 2012, 2014, 2015
  • AMWA Gender Equity Award, 2006-2007
  • Excellence in Teaching Award, NU Dept of Surgery, 2005, 2006, 2008, 2009, 2010, 2013, 2014, 2015, 2016
  • Association of Women Surgeons Outstanding Woman Resident Award, 2002
  • Society of Vascular Surgery Lifeline Award, 1999
  • Thoracic Surgery Foundation Nina Starr Braunwald Research Fellowship, 1999-2000
  • American Society of Gene Therapy Young Investigators Award, 1998
  • Society of University Surgeons/Ethicon Resident Research Fellowship, 1998-1999
  • American Medical Women’s Association Award, 1994
  • Alpha Omega Alpha, 1993

Find publications on PubMed