Melissa Orenduff

BSPH
Predoctoral Fellow
Nutritional Biochemistry

Research Interests

My current research is focused on the tumour-suppressive role of insulin-like growth factor binding protein 7 (IGFBP7) in pancreatic cancer. IGFBP7 is modulated by dietary energy balance and may be a potential intervention target for preventing pancreatic cancer.

Prior to graduate school, I was a research coordinator at Duke University Medical Center.  As a coordinator, I was involved with several clinical research projects investigating the impact of weight loss interventions and protein supplementation in older adults.

Since 2012, I have been the Managing Editor for the Journal of Nutrition in Gerontology and Geriatrics. 

Selected Publications

 

  • Porter Starr KN, Orenduff M, McDonald SR, Mulder H, Sloane R, Pieper CF, Bales CW. Influence of Weight Reduction and Enhanced Protein Intake on Biomarkers of Inflammation in Older Adults with Obesity. Journal of Nutrition in Gerontology and Geriatrics (Special Issue). In Press 2019.
  • Payne ME, Porter Starr KN, Orenduff M, Mulder HS, McDonald SR, Spira AP, Pieper CF, Bales CW. Quality of life and mental health in older adults with obesity and frailty: Associations with a weight loss intervention. J Nutr Health Aging. 2018; https://doi.org/10.1007/s12603-018-1127-0.
  • Porter Starr KN, McDonald SR, Jarman A, Orenduff M, Sloane R, Pieper CF, Bales CW. Markers of Renal Function in Older Adults Completing a Higher Protein Obesity Intervention and One Year Later: Findings from the MEASUR-UP Trial. Journal of Nutrition in Gerontology and Geriatrics. 2018; 37:2, 117-129, DOI: 10.1080/21551197.2018.1478696.
  • Porter Starr KN, Mulder H, Orenduff M, Pieper CF, Huffman KM, McDonald S, Bales CW. Influence of Protein Intake During Weight Loss on Inflammatory Response of Obese, Frail Older Adults. Innovation in Aging. 2017; 1. 216-217. 10.1093/geroni/igx004.813.
  • Bales CW, Porter Starr KN, Orenduff M, McDonald S, Molnar K, Jarman A, Onyenwoke A, Mulder H, Payne M, Pieper C. Influence of Protein Intake, Race, and Age on Responses to a Weight-Reduction Intervention in Obese Women. Curr Dev Nutr. 2017; 1(5):e000703.
  • Porter Starr KN, Pieper CF, Orenduff  MC, McDonald SR, McClure LB, Zhou R, Payne ME, Bales CW. Improved Function with Enhanced Protein Intake per Meal: A Pilot Study of Weight Reduction in Frail Obese Older Adults. J Gerontol A Biol Sci Med Sci. 2016; 71(10):1369-75.PMID: 26786203.
  • McDonald SR, Starr KNP, Mauceri L, Orenduff M, Granville E, Ocampo C, Payne ME, Pieper CF, Bales CW. Meal-based enhancement of protein quality and quantity during weight loss in older adults with mobility limitations: Rationale and Design for the MEASUR-UP trial. Controlled Clinical Trials. 2015; 40, 112-123. PMID: 25461295.
  • Payne ME, Starr KP, Mauceri L, McDonald SR, Orenduff MC, Pieper CF. Depression Symptoms in Obese Older Adults with Functional Limitations: Effects of a Weight-Loss Intervention. Journal of Women’s Health. 2014; 23(10):868-868.

Mentor

Stephen Hursting