Assistant Professor, School of Pharmacy
Area of Interest
- Mechanistic exploration of molecular determinants of heterochromatin formation and epigenetic memory, using chemical induced proximity (CIP) to recruit defined epigenetic regulators to chromatin in vivo assay (CiA) reporter systems in mammalian cells.
- Drug discovery campaigns to identify inhibitors of epigenetic pathways with relevance to human disease, using a focused epigenetically targeted compound set to run two distinct chromatin-based functional screens followed by molecular target identification and exploration of mechanism-of-action.
- Gene specific regulation of endogenous disease-relevant loci with chemical epigenetic modifiers (CEM)s, which harness endogenous epigenetically active enzymes and recruit them to specific genes targeted by deactivated Cas9 (dCas9).
Awards and Honors
2017 CBMC Teaching Recognition Recipient
2017 IBM Junior Faculty Development Award
2016 CBMC Teaching Recognition Recipient
2016 AACP – New Investigator Award Recipient
2001 Undergraduate degree with distinction magna cum laude
2000 Michelson-Morley Research Competition 1st Place