PhD, MPH
Professor, Nutrition
UNC Gillings School of Global Public Health
UNC-Chapel Hill
Cancer Epidemiology
Area of Interest
Stephen Hursting, PhD, MPH, is an international leader in the area of nutrition, obesity, metabolism and cancer. His lab focuses on the molecular and metabolic mechanisms underlying obesity-cancer associations, and the impact of obesity- energy balance modulation (eg, calorie restriction and exercise) or pharmacologic agents on cancer development, progression, and responses to chemotherapy. Primarily using genetically engineered mouse models of breast cancer (recently in parallel with several clinical trials), colon cancer and pancreatic cancer, Hursting has identified the IGF1/Akt/mTOR and NF-kB signaling pathways as key targets for breaking the obesity-cancer link. His publications establish causal links between obesity, cancer and several systemic factors (including IGF-1, insulin, leptin and IL-6) and components of their downstream signaling pathways (including mTOR and NF-kb).
Awards and Honors
- Plenary Speaker, International Agency for the Study of Obesity-Nutrition and Cancer Conference, Valencia, Spain, 2010
- World Cancer Research Fund/American Institute for Cancer Research, Continuous Update Panel member, 2010-present
- Keynote Speaker, Johns Hopkins University Breast Cancer Program Retreat, Baltimore, MD, June 2010
- NIH Merit Award for Excellence in the Measurement, Analysis, and Release of Nationally Representative Data On Serum Biomarkers From The Insulin-Like Growth Factor Axis, 2009
- Co-Chair, American Association for Cancer Research National Meeting, 2009
- World Cancer Research Fund/American Institute for Cancer Research. Mechanisms Working Group Co-Chair for Expert Report: Food, Nutrition, Physical Activity and the Prevention of Cancer: A Global Perspective, 2004-2007
- Malcolm Trout Nutritional Science Award, Michigan State University, 2007
- NIH Merit Award for Leadership/Excellence in Obesity and Cancer Research, 2005
News and Stories
UNC Lineberger and UNC faculty and trainees present findings at AACR annual meeting
Nearly 30 UNC Lineberger and UNC faculty and trainees will present findings and participate during the American Association for Cancer Research annual meeting in Chicago, April 25-30.
UNC researchers present at American Association for Cancer Research’s 115th Annual Meeting
Researchers and trainees from UNC and UNC Lineberger at will present more than 30 talks and participate in scientific and educational panels and discussions on the latest cancer research.
