Events at UNC Lineberger Comprehensive Cancer Center
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POSTPONED — UNC Lineberger Special Seminar: From Transcriptional Rewiring to Therapeutic Opportunities – Targeting MDM2 Amplifications in Cancer
This seminar has been postponed.
Samantha Bevill, PhD, is a pharmacologist specializing in the mechanisms of therapeutic resistance in aggressive cancers.
She earned her BS in Microbiology from Clemson University and her PhD in Pharmacology from the University of North Carolina at Chapel Hill.
Under the mentorship of Dr. Gary Johnson, her doctoral research utilized advanced proteomics and genomics to map compensatory kinase signaling pathways in breast cancer. Currently, as a postdoctoral fellow in Dr. Bradley Bernstein’s laboratory, Dr. Bevill investigates the transcriptional regulatory landscapes of aggressive sarcomas. Her work has uncovered a novel role for MDM2 in driving therapeutic resistance.
Dr. Bevill’s most recent work, which is co-advised by Dr. Jun Qi, bridges basic mechanistic discovery and therapeutic application, developing chemical biology strategies to leverage MDM2’s E3 ligase activity for tumor-specific protein degradation
