gPATH Pre-clinical Genomic Pathology Laboratory

The Lineberger Comprehensive Cancer Center’s (LCCC) Pre-Clinical Genomic Pathology Lab (gPATH) is a medium throughput facility providing comprehensive genomic services for investigators by employing Next Generation Sequencing (NGS) and/or NanostringTM technology. The mission of the Pre-Clinical Pathology Laboratory is to supports translational human cancer genomics research at the University of North Carolina – Chapel Hill. The gPATH facility performs bio sample processing and analyses for the molecular pathologic and genomic characterization of patient-derived specimens in preclinical research projects and clinical protocols. Our laboratory employs highly-automated, as well as manual, platforms for reproducible medium-throughput nucleic acid extraction, library preparation, and next-generation sequencing of tissue, cells and blood samples. Our goal is to provide a resource that balances rigor and flexibility to meet the needs of academic and clinical research, and that can ultimately produce optimized and validated processes for adoption in clinical labs.

In the News

UNC Lineberger to partner in $12 million effort to find treatments for genetically-linked cancers


J. Todd Aumon, PhD

UNC School of Medicine
105 MacNider Hall
Chapel Hill NC 27599


Pathology and Laboratory Medicine