This workshop highlights the power of smaller eukaryotes (e.g., yeast and flies) to uncover basic principles of cell biology, and thus, how discoveries made in these organisms have led the way in our understanding of disease pathways. We also cover how model organisms have been a powerful tool for drug discovery. ITCMS fellows are encouraged … Read more
This workshop focuses on defining general aspects and approaches to drug discovery, the challenges and opportunities in academic drug discovery, and case histories of drug and probe discovery at UNC. It is led by ITCMS preceptor Stephen Frye, Director of the Center for Integrative Chemical Biology and Drug Discovery, UNC Eshelman School of Pharmacy. He … Read more
Proteomics (elective) - This workshop covers the basic principles, experimental design, and data analysis platforms for protein mass spectrometry experiments. Discussion topics include highlights of several upstream biochemical approaches, an overview of peptide fractionation by liquid chromatography, and the inner workings of ion trap mass spectrometers, including principles of ion detection and fragmentation. Lastly, the … Read more
