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Clinical trials help doctors find better ways to treat and prevent cancer. If you or a loved one has cancer, you might consider joining a clinical trial in order to try a new drug or treatment, or help doctors develop better treatments for the future. Learn more about clinical trials

Browse our list of lymphoma clinical trials below, or search our clinical trials database by cancer type, drug, doctor, or protocol.

Disease Study # Study Title and Description PI
Relapsed/Refractory E4412-CIRB A Phase I Study with an Expansion Cohort/Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Hodgkin Lymphoma Anne Beaven, MD
Relapsed/Refractory LCCC1606-ATL Phase I Study of the Administration of T lymphocytes Co-Expressing the CD30 Chimeric Antigen Receptor (CAR) and CCR4 for Relapsed/Refractory CD30+ Hodgkin Lymphoma and CD30+ Non-Hodgkin Lymphoma Natalie Grover, MD
Relapsed LCCC1606-ATL Phase I Study of the Administration of T lymphocytes Co-Expressing the CD30 Chimeric Antigen Receptor (CAR) and CCR4 for Relapsed/Refractory CD30+ Hodgkin Lymphoma and CD30+ Non-Hodgkin Lymphoma Natalie Grover, MD
Relapsed (HIV) AMC-095 A Phase I Study of Ipilimumab and Nivolumab in Advanced HIV Associated Solid Tumors with an Expansion Cohort in HIV Associated Solid Tumors and a Cohort of HIV-Associated Classical Hodgkin Lymphoma Christopher Dittus, DO, MPH
Frontline S1826-CIRB A Phase III, Randomized Study of Nivolumab (Opdivo) Plus AVD or Brentuximab Vedotin (Adcetris) Plus AVD in Patients (Age greater than or equal to 12 years) with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma Natalie Grover, MD
Relapsed/Refractory LCCC 1852-ATL A Prospective Pilot Study Assessing the Immunomodulatory Effect and Clinical Activity of Programmed Cell Death Protein 1 Inhibition Following CD30 Directed Chimeric Antigen Receptor T Cell Therapy in Relapsed/Refractory Classical Hodgkin Lymphoma Natalie Grover, MD

Disease Study # Study Title and Description PI
Relapsed/Refractory LCCC1811-ATL Phase 1 Study of the Administration of T lymphocytes Expressing the Kappa Chimeric Antigen Receptor (CAR) and CD28 Endodomain for Relapsed/Refractory Kappa+ Mantle Cell and Indolent Non-Hodgkin Lymphoma Natalie Grover, MD
Relapsed/Refractory LCCC1813-ATL A Phase I Study of Autologous Activated T-cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch in Subjects with Relapsed/Refractory B-cell Lymphoma Natalie Grover, MD
Relapsed/Refractory LOXO-BTK-18001 A Phase 1/2 Study of Oral LOXO-305 in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) or Non-Hodgkin’s Lymphoma (NHL) Catherine Coombs, MD

Disease Study # Study Title and Description PI
Frontline EA4151-CIRB A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma In Minimal Residual Disease-Negative First Complete Remission Anne Beaven, MD
Frontline EA4181-CIRB A Randomized 3-Arm Phase II Study Comparing 1.) Bendamustine, Rituximab and High Dose Cytarabine (BR/CR) 2.) Bendamustine, Rituximab, High Dose Cytarabine and Acalabrutinib (BR/CR-A), and 3.) Bendamustine, Rituximab and Acalabrutinib (BR-A) in Patients < or = 70 years old with Untreated Mantle Cell Lymphoma. Anne Beaven, MD
Relapsed AFT-32 A Phase II Study of Palbociclib (PD-0332991) in Combination with Ibrutinib in Patients with Previously Treated Mantle Cell Lymphoma Anne Beaven, MD

Disease Study # Study Title and Description PI
Relapsed/ Refractory LCCC 1841 A Phase II Trial of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas Christopher Dittus, DO, MPH
Frontline PCNSL LCI-HEM-PCNSL-RMPV-011 A Phase 1B Trial of Nivolumab Consolidation Following Completion of High Dose Methotrexate Containing Induction Chemotherapy in Older (Greater Than or Equal to 65 years) Patients with Previously Primary CNS Lymphoma Christopher Dittus, DO, MPH

Disease Study # Study Title and Description PI

Frontline

AMC-101 A Pilot Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas (ARL) Christopher Dittus, DO, MPH

Any (HIV)

AMC-083 Tissue Acquisition for Analysis of Prognostic Factors, Immunology, and Genetic Progression of HIV-1 Associated Malignancies Christopher Dittus, DO, MPH
Frontline (DEL or DHL) A051701 Randomized phase II/III study of venetoclax (ABT-199) plus chemoimmunotherapy for MYC/BCL2 double-hit and double expressing lymphomas Christopher Dittus, DO, MPH

Disease Study # Study Title and Description PI

Frontline

LCCC1637

Brentuximab Vedotin with Cyclophosphamide, Doxorubicin, Etoposide, and Prednisone (BV-CHEP) for the treatment of Adult T-Cell Leukemia/Lymphoma: A Phase II Trial of the Rare Lymphoma Working Group Christopher Dittus, DO, MPH
Relapsed/Refractory LCCC1904-ATL Phase II Study of the Administration of T Lymphocytes Expressing the CD30 Chimeric Antigen Receptor (CAR) for Relapsed/Refractory CD30+ peripheral T Cell Lymphoma Anne Beaven, MD

Disease Study # Study Title and Description PI
Relapsed LCCC1606-ATL Phase I Study of the Administration of T lymphocytes Co-Expressing the CD30 Chimeric Antigen Receptor (CAR) and CCR4 for Relapsed/Refractory CD30+ Hodgkin Lymphoma and CD30+ Non-Hodgkin Lymphoma Natalie Grover, MD

Disease Study # Study Title and Description PI
Frontline S1826-CIRB A Phase III, Randomized Study of Nivolumab (Opdivo) Plus AVD or Brentuximab Vedotin (Adcetris) Plus AVD in Patients (Age greater than or equal to 12 years) with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma Natalie Grover, MD
Relapsed/Refractory E4412-CIRB A Phase I Study with an Expansion Cohort/Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Hodgkin Lymphoma Anne Beaven, MD

Disease Study # Study Title and Description PI

Frontline

AMC-101 A Pilot Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas (ARL) Christopher Dittus, DO, MPH

Any (HIV)

AMC-083 Tissue Acquisition for Analysis of Prognostic Factors, Immunology, and Genetic Progression of HIV-1 Associated Malignancies Christopher Dittus, DO, MPH
Relapsed (HIV) AMC-095 A Phase I Study of Ipilimumab and Nivolumab in Advanced HIV Associated Solid Tumors with an Expansion Cohort in HIV Associated Solid Tumors and a Cohort of HIV-Associated Classical Hodgkin Lymphoma Christopher Dittus, DO, MPH