Clinical Trials
A selective listing of clinical trials for brain and central nervous system cancers that are currently available at UNC Lineberger Comprehensive Cancer Center.
| Study Phase | Study # | Study Title and Description | Principal Investigator |
|---|---|---|---|
| Phase II | A071401-CIRB | Phase II Trial of SMO/AKT/NF2 inhibitors in Progressive Meningiomas with SMO/AKT/NF2 Mutations | Frances Collichio, MD |
| Phase III | EF-25 | Pivotal, Open-Label, Randomized Study of Radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC) | |
| Phase III | OT-15-001 | A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy | |
| Phase III | NCT02831959 | Effect of TTFields (150 kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS) |