A selective listing of clinical trials for brain and central nervous system cancers that are currently available at UNC Lineberger Comprehensive Cancer Center.
|Study Phase||Study #||Study Title and Description||Principal Investigator|
|Phase II||A071401-CIRB||Phase II Trial of SMO/AKT/NF2 inhibitors in Progressive Meningiomas with SMO/AKT/NF2 Mutations||Frances Collichio, MD|
|Phase III||EF-25||Pivotal, Open-Label, Randomized Study of Radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC)|
|Phase III||OT-15-001||A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy|
|Phase III||NCT02831959||Effect of TTFields (150 kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS)||Simon Khagi, MD|