Andrew Wang, MD, assistant professor of radiation oncology, has been awarded a $50,000 one-year grant from the Lung Cancer Research Foundation.
Wang is a member of UNC Lineberger Comprehensive Cancer Center.
The grant will fund research into the use of nanoparticles for drug delivery of DNA double-strand break repair inhibitors (DSBRIs) in combined chemotherapy and radiation therapy treatment of non-small cell lung cancer. DSBRIs can sensitize cancer cells to both chemotherapy and radiation therapy, but need to be delivered selectively to cancer cells, while sparing normal cells. Dr. Wang’s lab will test nanoparticle formulations of DSBRIs and evaluate their effectiveness in laboratory models.