Researchers review metastatic melanoma treatment

February 15, 2019

Researchers led by UNC Lineberger’s David Ollila, MD, FACS, the James H. and Jesse E. Millis Distinguished Professor in the UNC School of Medicine Division of Surgical Oncology, reviewed the results for 80 adult metastatic melanoma patients treated with talimogene laherparepvec, or TVEC. Injection of TVEC effectively treated almost 40 percent of patients with tumors … Continued

Lineberger Club features ovarian cancer survivor, advocate

February 15, 2019

While Marie Wood felt like she had just been to war, still, she was happy. After a diagnosis of ovarian cancer, surgery and six months of chemotherapy, the Greensboro resident, mother of four and successful interior designer learned her cancer was in remission. Life was good. She had just wrapped up the holidays with her … Continued

UNC-led team awarded $5.1M for cervical cancer prevention effort in Malawi

February 6, 2019

The United States Agency for International Development, in partnership with the U.S. National Academies of Science, Engineering, and Medicine, will fund two new programs to prevent cervical cancer in sub-Saharan Africa, including a project led by UNC scientists and physicians in Malawi.

UNC, Ribisl among the highest ranked producers of scientific papers on e-cigarettes

February 5, 2019

Researchers at the University of North Carolina at Chapel Hill published the third most number of scientific publications about electronic cigarettes between 2003-2018, according to a study published in the International Journal of Environmental Research and Public Health. The paper also cited UNC Lineberger’s Kurt Ribisl, PhD, as one of the most prolific e-cigarette scientists.

Der to receive mentorship award from Carolina

February 2, 2019

Channing Der, PhD, a member of the University of North Carolina Lineberger Comprehensive Cancer Center and the Sarah Graham Kenan Distinguished Professor of Pharmacology, will receive the “Mentor Award for Lifetime Achievement” at an awards banquet April 8. Der is one of 24 faculty members and teaching assistants who have been named winners of Carolina’s … Continued

Scientists uncover mechanism cells use to deactivate a signal that’s hyperactive in cancer

January 31, 2019

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have discovered how a cellular signal that’s abnormally hyperactive in cancer can be deactivated. In the journal Cell Reports, UNC Lineberger’s M. Ben Major, PhD, and colleagues published a paper on how the WNT signaling pathway is regulated. WNT proteins increase tumor onset, growth … Continued

Stand Up To Cancer names UNC Lineberger researchers to ‘Dream Team’

January 30, 2019

The multi-institutional team, which is co-led by UNC Lineberger’s Gianpietro Dotti, MD, and includes six UNC Lineberger researchers, will focus on developing chimeric antigen receptor T-cell (CAR-T) therapies to recognize and attack T-cell lymphoma, a group of rare cancers of the blood and immune system.

Researchers publish milestone review on the role of cell signaling proteins in cancer

January 29, 2019

University of North Carolina Lineberger Comprehensive Cancer Center scientist Antonio “Tony” Amelio, PhD, is not necessarily looking for the “smoking gun” of cancer biology, or one single cause of cancer. Instead, he’s looking into how a family of newly described proteins involved in the cellular stress response can cause a complex ripple effect of changes … Continued