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San Antonio Breast Cancer Symposium
From left: Yara Abdou, MD; Lisa A. Carey, MD, ScM, FASCO; Charles Perou, PhD; Philip Spanheimer, MD; Patty Spears; and Melissa Troester, PhD.

University of North Carolina Lineberger Comprehensive Cancer Center researchers and colleagues will be presenting the latest findings from basic, translational and clinical studies at the 45th annual San Antonio Breast Cancer Symposium, Dec. 6-10.

The longstanding international symposium, which was attended by more than 9,500 cancer research and care professionals from more than 100 countries last year, features presentations outlining study findings focused on advancing the prevention, diagnosis and treatment of breast cancer.

UNC Lineberger faculty, trainees and colleagues who will be presenting at the meeting include:




Stars at Night Ballroom 1&2  |  12-2 p.m. CT

Big Data and Health Equity

Moderators (from UNC Lineberger):
Charles Perou, PhD

Patty Spears



Hall 3  |  12-2 p.m. CT


Overcoming the Big Obstacles to Find Solutions for Breast Cancer



Patty Spears



Hall 3  |  2-5 p.m. CT


GS1-01 Race and clinical outcomes in the RxPONDER trial (SWOG S1007)

2-2:15 p.m. CT

Abdou Y, Barlow WE, Gralow JR, Meric-Bernstam F, Albain KS, Hayes DF, Lin NU, Perez EA, Goldstein LJ, Chia SK, Dhesy-Thind S, Rastogi P, Alba E, Delaloge S, Schott AF, Shak S, Sharma P, Lew DL, Miao J, Unger JM, Tripathy D, Pusztai L, Hortobagyi GN, Kalinsky K.


Presenter: Yara Abdou, MD (In addition to her oral presentation, Abdou will share her findings at a press conference on Tuesday, Dec. 6, 12:30-1:30 p.m.)


Poster Session

5 p.m. CT  |  Hall 1


P1-04-08 Independent validation of a novel, non-invasive approach to predict pathologic complete response (pCR) in a blinded, prospectively-run single center trial
Kuzmiak C, Hartman TS, Benefield T, Peterson J, Antony AK, Pandey T, Cole Jr JA, Calhoun BC, Carey LA.


Presenter: Tushar Pandey, MBA, SimBioSys


P1-06-04 Impacts of treatment delay on breast cancer mortality and benefit of timely care in black and non-black women
Jackson B, Wheeler S, Yanguela J, LeBlanc M, Kuo T-M, Baggett C, Reeder-Hayes K


Presenter: Bradford Jackson, PhD


Spotlight Poster Discussion

5 p.m. CT  |  Hemisfair Ballroom 1&2


PD1-08 PAM50 and 21-gene recurrence scores in younger and Black women with breast cancer
Vohra S, Van Alsten S, Ivory JM, Hamilton A, Gao X, Kirk E, Nsonwu-Farley J, Butler E, Taffe B, Perous CM, Carey LA, Troester M.


Presenter: Melissa Troester, PhD




Poster Session

7 a.m. CT  |  Hall 1


P2-12-01 A comprehensive assessment of researcher needs to increase biospecimen donations for breast cancer research: A Patients and Researchers Together (PART) Program


Morris H, Van Lokeren M, Spears PA, Potter JA, Branch V, Patient and Researchers Together Team, Perou CM, Carey LA.


Presenter: Patty Spears


Spotlight Poster Discussion

7 a.m. CT  |  Hemisfair Ballroom 1&2


PD4-08 A novel single cell model of Tamoxifen response in primary human breast tumors
Hyunsoo K, Whitman A, Wisniewska K, Garcia-Recio S, Kakati R, Franco HL, Perou CM, Spanheimer P.


Presenter: Philip Spanheimer, MD


PD4-09 Single cell RNA-sequencing identifies intra-tumoral cellular heterogeneity and drug-induced subpopulation shifts in triple negative breast cancer mouse models
Glodowski C, Mott KR, Okumu D, East MP, Elston TC, Johnson GL, Perou CM.


Presenter: Cherise Glodowski, MPhil



2022 AACR Distinguished Lectureship in Breast Cancer Research

12:30 p.m. CT  |  Hall 3


“Quantitative Medicine for Breast Cancer Patients”

Charles M. Perou, PhD


Clinical Controversies

2-3 p.m. CT  |  Hall 3



Lisa A. Carey, MD, ScM, FASCO


Educational Session

3-5 p.m. CT  |  Hemisfair Ballroom 1&2


Patient Advocate Perspective:

Patty Spears




Poster Session

5 p.m. CT  |  Hall 1


P5-14-02 Identifying oncogenic enhancer elements in TNBC of the Basal-like subtype using single-cell ATAC-seq and RNA-seq

Regner M, Thennavan A, Wisniewska K, Garcia-Recio S, Mendez-Giraldez R, Spanheimer P, Perou CM, Franco HL.


Presenter: Matthew Regner




Poster Session

7 a.m. CT  |  Hall 1


P6-06-01 Development of a patient advocate training at UNC’s Lineberger Comprehensive Cancer Center

Kennedy KL, Mejia AM, Walton EK, Freeman J, Lu A, Potter JA, Spears PA.


Presenter: Patty Spears


P6-12-03 Proinflammatory and estrogen signaling modulates the chemoresistance and metastasis of breast cancer cells through post-translational modifications of pioneering factor FOXA1

Li S, Franco HL, Kim H, Plagens RN, Mendez-Giraldez R, Tubbs C, Malladi V, Garay J.


Presenter: Shen Li, PhD


P6-12-08 Identifying FOXA1 binding partners using proximity labeling

Plagens R, Li S, Mills CA, Herring L, Franco HL.


Presenter: Rosemary Plagens, PhD


View from the Trenches: What will You do on Monday Morning

5:15 – 7:15 p.m. CT  |  Stars at Night Ballroom 1&2


Panel Member

Vernal Branch

UNC Lineberger Patient Advocate