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UNC Lineberger researchers J. Mauro Calabrese and Kevin M. Weeks were co-corresponding authors of a paper published in the Proceedings of the National Academy of Sciences.

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J. Mauro Calabrese is a UNC Lineberger member and an assistant professor in the UNC School of Medicine Department of Pharmacology.
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Kevin M. Weeks is a UNC Lineberger member and Kenan Distinguished Professor in the UNC-Chapel Hill Department of Chemistry.

The paper, “SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the 8IST lncRNA in living cells,” explored the function of a certain non-coding section of RNA called that’s essential for X-chromosome inactivation during female eutherian mammalian development.

To read the paper online, click here.